THE INSIDE PRESSURE OF STENT TUBE ON CHOLEDOCO-JEJUNOSTOMY SCAR:A STUDY ON SCAR TISSUE COLLAGEN

Ｒ啨ｓｕｍ啨　　 Ｏｂｊｅｃｔｉｆ　Ｃｏｍｍｅｌ ｅｆｆｅｔｂ啨ｎ啨ｆｉｃｉａｉｒｅｓｕｒｌａｃｉｃａｔｒｉｃｅｃｕｔａｎ啨ｅｓｏｕｓｂａｎｄａｇｅｃｏｍｐｒｅｓｓｉｆ ,ｓｔｅｎｔｔｕｂｕｌａｉｒｅｅｎｄｏｃｈｏｌｅｄｏｑｕｅｐｏｕｒｒａｉｔａｖｏｉｒｌｅｍ毢ｍｅｅｆｆｅｔｓｕｒｌａｃｉｃａｔｒｉｃｅｓｐｌａｎｃｈｎｉｑｕｅ .Ｌ ｅｘｐｅｒｉｅｎｃｅｅｓｔ劋ｃｈｅｒｃｈｅｒｌｅｔｅｍｐｓｏｐｔｉｍｕｍ ｐｏｕｒａｖｏｉｒｌａｆｏｒｍａｔｉｏｎｃｉｃａｔｒｉｃｉｅｌｌｅａｕｍｉｎｉｍｕｍ .　Ｍ啨ｔｈｏ…

THE INSIDE PRESSURE OF STENT TUBE ON CHOLEDOCO-JEJUNOSTOMY SCAR: A STUDY ON SCAR TISSUE COLLAGEN

Objective As the beneficial effect to the skin scar under external bandage compression, intra-choledocal stent must have the same effect on splanchnic scar formation. The experiment consists to work out the time optimum to yield a minimum scar formation. Methods By means of transmitting electronic microscope (TEM), computer assisted three-dimensional morphometry (CAM), and biochemical analysis to determine the extracellular collagen volume density (ECVD) and biochemical collagen content (BCC), to analyze the ultrastructure and components within scar tissues removed from the specimens in 3 groups of experimental animals were detailed. Results In the animals of simple choledoco-jejunostomy (CJ) group, active scar proliferation was seen in all specimens excised within one year after operation. In the stent group, decreasing collagen fibers arranged in orientation began to appear in the 6-month specimens and scar maturation existed in the 9- and 12-month specimens. In periodic tube withdrawal group, 3 months following tube ablation, scar proliferation recurred in the 6th month tube retaining animals, whereas scar maturation without recurrence happened in animals following 9 to 12 months tube retaining. Conclusion 9～12 months of tube stent is necessary for stable scar maturation.