腭咽成形术对阻塞性睡眠呼吸暂停低通气综合征患者生命质量的影响

目的探讨悬雍垂腭咽成形术（UPPP）对阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者生命质量的影响。方法 37例OSAHS患者实施H-UPPP治疗,分别于治疗前和治疗后6个月进行多导睡眠监测及生命质量评估。对照组为54例接受CPAP治疗患者。结果术前两组患者平均呼吸暂停低通气指数（AHI）及最低血氧饱和度（LSaO2）分别为（43.26±7.24）次/h、（78.62±10.48）%;（35.28±6.37）次/h、（81.73%±12.15）%;治疗后分别为（21.03±12.89）次/h、（83.96±7.52）%;（9.65±5.10）次/h、（87.26±6.30）%,两组患者治疗前后差异有显著性（P〈0.05）,提示CPAP组优于H-UPPP组。生命质量评估中,H-UPPP组躯体疼痛维度在手术前后无差异（P〉0.05）,其余各维度均明显改善;CPAP组患者治疗前后各维度均有显著性改善（P〈0.05）。结论 H-UPPP能显著降低AHI,改善生命质量;CPAP在临床疗效、改善躯体疼痛、精力等方面优于UPPP。

Quality of life in patients with obstructive sleep apnea hypopnea syndrome treated with uvulopalatopharyngoplasty

Objective To evaluate the quality of life(QOF) in patients with obstructive sleep apnea hypopnea syndrome(OSAHS) treated by uvulopalatopharyngoplasty(UPPP).Methods 91 cases of patients with OSAHS were included in this study,37 accepted for UPPP,and 54 for continous positive airway pressure(CPAP) as controll group.QOF Questionnaire and polysomnograhpy(PSG) were evaluated before and 6 months after treatment.Results The apnea hypopnea index(AHI) and lowest arterial oxygen saturation(LSaO2) in UPPP and CPAP group were(43.26±7.24)/h,(78.62±10.48)%;(35.28±6.37)/h,(81.73±12.15)%,respectively before treatment.AHI and LSaO2 were improved significantly after treatment(21.03±12.89)/h,(83.96±7.52)%;(9.65±5.10)/h,(87.26±6.30)%.In UPPP group the total QOL scores were improved significantly,except the body pain section.The total scores and all section of QOL were well improved in CPAP group.Conclusion The QOL,AHI,LSaO2 in the patients with OSAHS were well improved by UPPP or the treatment of CPAP.CPAP seem to be more effective than H-UPPP in,releasing body pain and improving vitality.