| 结核感染T细胞斑点试验及结核抗体在肺外结核病诊断中的临床意义 |
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| 引用本文： | 崔鲂,杨玲,孟江萍,向瑜.结核感染T细胞斑点试验及结核抗体在肺外结核病诊断中的临床意义[J].西部医学,2014(1):103-104,107. |
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| 作者姓名： | 崔鲂 杨玲 孟江萍 向瑜 |
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| 作者单位： | [1]重庆医科大学附属第一医院检验科,重庆400016 [2]重庆医科大学附属第一医院辅助生殖中心,重庆400016 |
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| 摘 要： | 目的探讨结核感染T细胞斑点试验（T-SPOT．TB）及抗结核抗体（38kD—IgG）试验在肺外结核病诊断中的临床价值。方法分析入院疑患肺外结核治疗的患者68例，其中确诊结核47例，非结核患者21例。用上述两种方法分别检测68例患者，并将二者的结果进行比较。结果T—SPOT．TB试验检测确诊结核病人的阳性率为78．7％（37／47）明显高于用结核抗体法检测确诊结核病人的阳性率59．5％（28／47）（P〈O．05）。二者的特异度分别为95．2％和71．4％，T—SPOT．TB检测特异度明显高于结核抗体检测（p〈0．05）。结论T-SPOT．TB检测是诊断肺外结核的快速敏感方法，在肺外结核性疾病诊断中有重要价值，可作为临床结核病的有效辅助诊断手段。
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| 关 键 词： | 结核 结核感染T细胞斑点试验 结核抗体 |
Clinical value of T-cell enzyme- linked lmmqnospot assay and tuberculosis antibody in the diagnosis of extrapulmonary tuberculosis |
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| Institution: | CUI Fang , YANG Lin , MENG Jiang-ping, et al (1. Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China 2. Assisited Reproductive Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China) |
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| Abstract: | Objective To evaluate the application value of T-cell enzyme- linked Immqnospot assay （T-SPOT. TB） and tuberculosis antibody used for clinical diagnosis of extrapulmonary tuberculosis. Methods 69 patients with tubercu- losis were detected with T-cell enzyme- linked Immqnospot assay and tuberculosis antibody. Results The positive rate of T-SPOT. TB was 78.7% （37/47）, which was higher than that of tuberculosis antibody （59. 5%） （P〈0.05）. Conclusion The T- SPOT. TB test has a higher sensitivity and specificity than tuberculosis antibody. It can be used as the effective auxiliary diagnosis methods of extrapulmonary tuberculosis. |
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| Keywords: | Tuberculosis Tuberculosis infection of T cells spot test Tuberculosis antibody |
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