药品不良反应121例报告分析

目的了解药品不良反应（ADR）发生特点及其引发的相关因素，促进临床合理用药。方法对121例ADR报告分别从药物种类、给药途径及患者年龄等方面进行统计分析。结果121例不良反应中，涉及抗菌药物67例，占55．37％；中药注射剂11例，占9．09％；静脉给药引起的不良反应103例，占85．12％。结论合理使用抗菌药物和中药注射剂，加强对中药注射剂的质量监测，以避免或减少ADR重复发生。

Analysis of 121 cases of adverse drug reactions

Objective To understand the characteristics of adverse drug reaction （ADR） in our hospital, and promote the rational use of drugs in clinic. Methods The 121 ADR cases had been collected from Jan. 1. 2008 to Dem. 31. 2008 in our hospital. All the cases were analyzed in respect of drug species, categories of drugs, adiministration and the patients＇ age. Results Of 122 ADR cases, there were 67 cases （55.37%） with antibiotics and 11 cases （9.09%） with traditional Chinese medicine. ADR induced by intravenous injection were 103 cases （85.12%）. ADR were mainly manifested as skin and its appendages. Conclusion Rational use of anti-infective drugs and the good quality of the traditional Chinese medicine injection should be emphasized to decrease the occurrence of ADR.