缩宫素联合欣母沛防治高危产妇剖宫产术后出血的疗效观察

目的 观察缩宫素联合欣母沛防治高危产妇剖宫产术后出血的疗效.方法 按入院先后顺序,将178例有产科剖宫产指征、具产后出血潜在因素的高危产妇随机分为观察组和对照组各89例.在胎儿娩出后,对照组给予静滴缩宫素20 U及宫体注射缩宫素20 U,如宫缩仍不佳,继续应用缩宫素20 U;而观察组给予静滴缩宫素20 U及宫体注射欣母沛250μg,如宫缩仍不佳则间隔15 min继续应用欣母沛250μg.比较两组术后2、24 h的出血量及产后出血的发生率.结果 产后2、24 h的出血量,观察组（221.3±59.7）ml和（299.1±72.8）m1]明显低于对照组（358.3±62.7）ml和（457.5±82.9）ml];产后出血发生率,观察组（19.1％）亦低于对照组（42.7％）,组间差异均有统计学意义（均P＜0.05）.结论 具产后出血高危因素的剖宫产患者,应用静脉滴注缩宫素的同时宫体注射欣母沛,可预防和治疗产后出血,并具有快速、安全的特点,具有重要临床价值.

Oxytocin combined with hemabate for prevention of high-risk cesarean section postpartum hemorrhage

Objective To explore the clinical efficacy of oxytocin combined with hemabate for the prevention of maternal risk factors for postpartum hemorrhage hemorrhage after cesarean section.Methods By order of admission,178 cases of obstetric indications for cesarean section with a potential risk factor of maternal postpartum hemorrhage were randomly divided into observation and control groups （n =89）.After delivery of the fetus in cesarean section,the control group received intravenous drip of oxytocin 20 U and uterus injection of oxytocin 20 U,such as contractions still poor continues to apply oxytocin 20 U,while observation group were given intravenous drip of oxytocin 20 U and uterus injection Hemabate 250μg,such contractions are still poor,the interval 15 min to continue to apply Hemabate 250μg.2,24 h postoperative blood loss and the incidence of postpartum hemorrhage were observed.Results The amount of bleeding postpartum 2,24 h of the observation group were （221.3±59.7） ml and （299.1 ± 72.8） ml,which were significantly lower than that of the control group （358.3±62.7） ml and （457.5±82.9）ml.The incidence of postpartum hemorrhage of the observation group （19.1％） was lower than that in the control group （42.7 ％） （P＜0.05）.Conclusion The intravenous oxytocin and uterus injection hemabate can prevent and treat postpartum hemorrhage.