硬膜外阻滞与椎旁阻滞在带状疱疹神经痛治疗中的疗效比较

目的比较椎旁阻滞与硬膜外阻滞在治疗带状疱疹神经痛患者的有效性和安全性。方法60例带状疱疹神经痛患者随机分成两组，椎旁组（P组）和硬膜外组（E组），每组30例，年龄25～80岁，分别、分次行椎旁阻滞及硬膜外阻滞治疗，并记录视觉模拟评分（visual analogue scale，VAS）的变化、后遗神经痛发生率和并发症发生率。结果P组与E组治疗效果无显著性差异。后遗神经痛发生率P组与E组治疗无显著性差异。并发症发生率P组少于E组。结论椎旁阻滞与硬膜外神经阻滞在治疗带状疱疹神经痛方面效果无显著性差异。但具有更大的安全性。

Comparison between epidural block and paravertebral block in treatment of postherpetic neuralgia

Objective To evaluate the efficacy and the safety of epidural block and paravertebral block in treatment of postherpetic neuralgia. Methods 60 patients with postherpetic neuralgia were randomly divided into two groups, including Paravertebral block Group（Group P, 30 cases） and epidural block（Group E, 30 cases）. The variation about VAS （visual analogue scale）, incidence rate of post neuralgia and complications were observed. Results There was no significant differences between Group P and Group E in treatment efficacy and incidence of post neuralgia. The incidence of complications of Group P was lower than that of Group E. Conclusions In terms of the treatment efficacy, there is no significant differences between epidural block and paravertebral block in treatment of postherpetic neuralgia, but the former is more safe than the later.