首页 | 本学科首页   官方微博 | 高级检索  
检索        

牙源性角化囊肿上皮组织中Bcl-2蛋白的表达
引用本文:彭利伟,赵怡芳.牙源性角化囊肿上皮组织中Bcl-2蛋白的表达[J].郑州大学学报(医学版),2007,42(1):92-93.
作者姓名:彭利伟  赵怡芳
作者单位:1. 郑州大学口腔医学院口腔颌面外科,郑州,450052
2. 武汉大学口腔医学院口腔颌面外科,武汉,430079
摘    要:目的:观察牙源性角化囊肿(OKC)上皮组织中Bcl-2蛋白的表达,探讨其与OKC生长特性的关系.方法:采用免疫组织化学法检测10例OKC、10例含牙囊肿(DC)、10例单囊型成釉细胞瘤组织中Bcl-2蛋白的表达.结果:OKC中6例(60%)Bcl-2阳性着色,阳性着色位于基底层细胞.DC中1例(10%)Bcl-2阳性着色,UA中10例(100%)均呈Bcl-2阳性着色,3组间Bcl-2阳性表达率差异有统计学意义(P<0.05).结论:OKC基底层细胞Bcl-2的阳性表达,可能与OKC上皮增殖及其侵袭性生长有关.

关 键 词:牙源性角化囊肿  含牙囊肿  单囊型成釉细胞瘤  Bcl-2
收稿时间:2006-06-15
修稿时间:2006-06-15

Expression of Bcl-2 protein in epithelial tissue of odontogenic keratocyst
PENG Liwei,ZHAO Yifang.Expression of Bcl-2 protein in epithelial tissue of odontogenic keratocyst[J].Journal of Zhengzhou University: Med Sci,2007,42(1):92-93.
Authors:PENG Liwei  ZHAO Yifang
Abstract:Aim: To detect the expression of Bcl-2 protein in the epithelial tissue of odontogenic keratocysts (OKC).Methods: The expression of Bcl-2 in OKC (n=10), dentigerous cyst (DC) (n=10) and unicystic ameloblastoma (UA) (n=10) tissue was detected using immunohistochemistry. Results: The positive expression rate of Bcl-2 was 60% in OKC, 10% in DC, and 100% in UA. The positive rate of Bcl-2 expression was statistically different among the three groups (P<0.05). Conclusion: The positive expression of Bcl-2 in the basal cell layer of OKC may be related to the proliferation of OKC epithelium and its aggressive behavior.
Keywords:odontogenic keratocyst  dentigerous cyst  unicystic ameloblastoma Bcl-2
本文献已被 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号