原代心肌细胞肥大损伤模型的研究概述

心肌细胞肥大是一种常见的心脑血管疾病，严重危害人类健康，已受到越来越多的重视。研究其发病机制对心肌肥大的防治具有重要意义。实验模型的选择和构建则是其关键和核心，一个恰当的实验模型不仅能减少经济及人力的耗损，更重要的是能准确反映实验现象，达到实验目的。本文主要介绍目前常用的心肌肥大的原代细胞模型，以便为预防并治疗心室重构疾病提供借鉴。

Hypertrophy of rat myocardial cells injury model:a short discuss

Myocardiel hypertrophy,a common cardiovascular and cerebrovascular disease,has attracted more and more atten?tion worldwide in recent years. Investigation of its pathogenesis is important for its prevention and treatment. The choice and establish?ment of experimental models play a vital role in these investigations. A proper experimental model can not only reduce costs and labor , but also reflect the nature of the experimental phenomena,which helps to achieve adequate experimental purposes. In the review,we introduce a brief discussion of on currently used primary cellular model of myocardial hypertrophy to provide reference for ventricular remodeling diseases researches.