| 生物可降解经皮给药微针研究进展 |
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| 引用本文： | 黄乾峰,林华庆,彭炳新,帅方舟.生物可降解经皮给药微针研究进展[J].国际药学研究杂志,2017,44(8). |
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| 作者姓名： | 黄乾峰 林华庆 彭炳新 帅方舟 |
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| 作者单位： | 广东药科大学广东省药物新剂型重点实验室, 广州,510006 |
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| 摘 要： | 微针是一种实现无痛和微创的给药新技术.其原理是穿刺皮肤产生微米级的给药通道,以增强皮肤对大分子药物的渗透性.生物可降解微针主要解决不可降解材料微针断裂于皮肤内造成的安全问题.本文对生物可降解微针的特点、可降解材料及其最新研究进展进行阐述,并分析其发展现状和趋势.
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| 关 键 词： | 微针 生物可降解材料 经皮给药 |
Biodegradable microneedles applied in the transdermal drug delivery:research advances |
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| HUANG Qian-feng,LIN Hua-qing,PENG Bin-xin,SHUAI Fang-zhou.Biodegradable microneedles applied in the transdermal drug delivery:research advances[J].Foreign Medical Sciences(Section of Pharmarcy),2017,44(8). |
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| Authors: | HUANG Qian-feng LIN Hua-qing PENG Bin-xin SHUAI Fang-zhou |
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| Abstract: | Microneedle is a painless and minimally invasive transdermal drug delivery. It can enhance the permeability of skin for macromolecular drugs by puncturing and creating a micron-level drug delivery channel in the skin. The biodegradable microneedles aim to solve the problem that nondegradable-material microneedles may break under skin and cause adverse reaction. This article pro?vides an overview of the characteristics of biodegradable microneedles,the biodegradable materials used,its recent research progress, the development status and the tendency. |
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| Keywords: | microneedle biodegradable material transdermal drug delivery |
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