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基于髓病主于肝胆辨治神经内分泌疾病
作者姓名:周德生  谢清  谭惠中  唐一华  刘利娟  陈瑶
作者单位:湖南中医药大学第一附属医院神经内科,湖南 长沙 410007;湖南中医药大学,湖南 长沙 410208
基金项目:国家自然科学基金资助项目(81874463);湖南省科技厅科技创新平台与人才计划(2017SK4005);湖南省中医药管理局资助项目(201824);湖南省级财政中医药项目-名院工程(rsk-010-13[006-09]);湖南中医药大学校级科研基金(ZYYDX201730);中医内科学重大疾病防治及成果转化-教育部重点实验室开放基金(ZYNK201609);湖南省科技厅重点专项(2017SK2111)。
摘    要:中医之髓,包括脑髓、脊髓、骨髓、五脏之髓,髓病包括脑髓病变及脏髓病变,髓系脑病表现为意识障碍、认知障碍、精神心理障碍、神经功能障碍等症状和体征,属于全身性疾病。基于髓系脑病理论,神经内分泌疾病具有临床症状的隐匿性和不典型性、病位的发散性和聚合性、病程的慢性进展和急性加重的病机特征。奇恒互藏,髓病与脑、胆、脉相关,髓病与五脏病变亦相关,临床表现多个脏腑同病,诸虚诸实并存,不同神经内分泌疾病的病位有一定的选择性和规律性。从肝胆寒热虚实辨治神经内分泌疾病,通过高泌乳素血症、库欣综合征2个医案,阐述了顾护阳气,少火生气;转运枢机,和法用药;补通并行,镇摄为佐;尚用风药及血肉有情之品等用药特色。

关 键 词:  髓系  髓病  髓系脑病  神经内分泌疾病  从肝胆辨治

Dialectical Treatment of Neuroendocrine Disease Based on Myeleterosis is Mainly in the Liver and Gallbladder
Authors:ZHOU Desheng  XIE Qing  TAN Huizhong  TANG Yihua  LIU Lijuan  CHEN Yao
Institution:(Department of Neurology,the First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha,Hunan 410007,China;Hunan University of Chinese Medicine,Changsha,Hunan 410208,China)
Abstract:Marrow in traditional Chinese medicine includes marrow of brain,spinal cord,bone and the five internal organs.Myelopathy includes encephalopathy and visceral myelopathy.Myeloid encephalopathy is a systemic disease characterized by consciousness disorder,cognitive disorder,mental and psychological disorder,neurological dysfunction and other symptoms and signs.Based on the theory of myeloid encephalopathy,neuroendocrine diseases have the pathogenesis characteristics of occult and atypical clinical symptoms,divergent and aggregation of disease location,chronic progression and acute exacerbation of disease course.Extraordinary organ is interconnectedness,myeleterosis is related to brain,gallbladder and pulse.Myelopathy is also related to five internal organs diseases.Clinical manifestations are multiple organs diseases coexist with deficiency and excess.The location of different neuroendocrine diseases has certain selectivity and regularity.From the liver-gallbladder cold and heat,deficiency and excess to dialectical treat neuroendocrine diseases,through two medical cases of hyperprolactinemia and Cushing syndrome,this paper explains medication characteristics of protect Yang qi and mild fire supplements qi;transport pivot and harmonize medication;unity of supplementing and unstopping and cooperate with heavy settling;still use wind medicine and medicinal with affinity to flesh and blood.
Keywords:marrow  myeloid  myeleterosis  myeloid encephalopathy  neuroendocrine disease  dialectical treatment based on the liver and gallbladder
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