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| 聚苯胺／金复合纳米纤维在大脑神经递质多巴胺检测中的应用 | |
| 引用本文： | 彭芳芳,郭志睿,张宇,顾宁.聚苯胺／金复合纳米纤维在大脑神经递质多巴胺检测中的应用[J].东南大学学报(医学版),2008,27(4). |
| 作者姓名： | 彭芳芳 郭志睿 张宇 顾宁 |
| 作者单位： | 1. 江苏省生物材料与器件重点实验室,江苏,南京,210096;东南大学,生物电子学国家重点实验室,江苏,南京,210096;东南大学,化学化工学院,江苏,南京,210096 2. 江苏省生物材料与器件重点实验室,江苏,南京,210096 3. 江苏省生物材料与器件重点实验室,江苏,南京,210096;东南大学,生物电子学国家重点实验室 |
| 基金项目： | 国家自然科学基金 , 国家重点基础研究发展计划(973计划) |
| 摘 要： | 目的:研究聚苯胺/金(PANI/Au)复合纳米纤维修饰电极能否高灵敏、高选择检测大脑神经递质多巴胺(DA)。方法:基于PANI/Au修饰电极,电化学方法检测DA的响应电流,脉冲伏安法分析DA和抗坏血酸(AA)共存下的情况。结果:PANI/Au修饰电极可以获得DA的响应电流分别是单纯PANI修饰电极和裸电极的1.5和2.4倍,并且检测到DA和AA的峰电位相差达260 mV。结论:PANI/Au复合纳米纤维修饰电极可以提高DA的检测灵敏度和选择性。 |
| 关 键 词： | 复合纳米纤维 多巴胺 聚苯胺 金纳米颗粒 抗坏血酸 电化学 |
Application of polyaniline/Au composite nanofibers on the detection of neuro-transmitter dopamine |
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| PENG Fang-fang,GUO Zhi-rui,ZHANG Yu,GU Ning.Application of polyaniline/Au composite nanofibers on the detection of neuro-transmitter dopamine[J].Journal of Southeast Univ: Medical Sci Ed,2008,27(4). | |
| Authors: | PENG Fang-fang GUO Zhi-rui ZHANG Yu GU Ning |
| Abstract: | Objective To study whether the polyaniline/Au(PANI/Au) composite nanofibers-modified electrode can be used to sensitively and selectively determine neuro-transmitter dopamine.Methods The electrochemical method was used to detect the response of current of DA based on PANI/Au composite nanofibers-modified electrode.The coexistent system of DA and AA was analyzed by differential pulse voltammetry.Results The PANI/Au composite nanofibers-modified electrode had obtained the electrocatalytic anodic current of DA 1.5-fold higher than the pure PANI-modified electrode did and 2.4-fold higher than the bare electrode did.And the separation between the voltammetric peaks of AA and DA was large(260 mV).Conclusion The PANI/Au composite nanofibers have been demonstrated to be able to promote the sensitivity and selectivity of the detection of DA. |
| Keywords: | composite nanofibers dopamine polyaniline Au nanoparticles ascorbic acid electrochemistry |
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