362名脂肪肝患者相关指标及相关疾病患病状况研究

目的 :探讨脂肪肝患者血清相关生化指标的变化以及高血压、肥胖和糖尿病的发生率。方法 :收集来自鼓楼医院体检中心 3 62名脂肪肝患者的体检资料 ,并与 3 62名健康体检者 (为对照组 ,年龄相差不超过 3岁 )的资料进行比较。结果 :脂肪肝患者体质指数 (BMI)高于对照组 ,同时血清中甘油三酯、总胆固醇、低密度脂蛋白胆固醇、载脂蛋白B、空腹血糖、丙氨酸转氨酶含量及血压 (收缩压及舒张压 )均值均高于对照组 ,而高密度脂蛋白胆固醇含量低于对照组。脂肪肝患者高血压、高血糖和肥胖的发生率高于对照组。结论 :脂肪肝的发生不仅与脂质代谢紊乱有关 ,与血糖、血压及BMI间也有联系 ,脂肪肝患者高血压、糖尿病、肥胖症的患病率高于健康人。

Study on the indexes related to fatty liver and the prevalence rates of related diseases of 362 fatty liver

Objective To explore the changes of the serum inde xes related to fatty liver an d the prevalence rates of the high blood pressure, obesity, and diabetes of the patients with fatty liver. Methods Physical examination data of 362 patients with fatty liver were collected in the Drum Tower hospital health examination center. These data were compared with the health examination data of 362 non-fatty live r people of sex-and age matched within 3 years according to the fatty liver cases. Results The body mass index (BMI) of the fa tty liver group was significantly higher than that of normal group. Meanwhile the differences of triglycerides (TG), total cholesterol (TCH), low density lipoprotein choleste rol (LDL-C), apolipoprotein B (Apo B), the blood glucose in empty stomach, alan ine aminotransferase (ALT), systolic blood pressure (SBP) and diastolic blood pr essure (DBP) between the fatty liver group and control group were significant. And the high density lipoprotein cholesterol (HDL-C) level of fat ty li ver patients was lower than that of control group. The prevalence rates of the high blood pressure, obesity, and diabetes of the patients with fatty liver were high er than that of control people. Conclusions The occurrence of f atty liver is related not only to the disturbance of lipid metabolism but als o to the blood gl ucose, blood pressure, and BMI. The prevalence rates of the high blood pressure , obesity, and diabetes of the patients with fatty liver are higher than those o f control people.