| 胰高糖素—胰岛素等治疗急性肝坏死—动物实验初步观察 |
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| 引用本文： | 于洋,张令志,黄洪志,姜诞宁,徐振武,汪伟业,秦洪义,刘潜心.胰高糖素—胰岛素等治疗急性肝坏死—动物实验初步观察[J].第二军医大学学报,1985(1). |
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| 作者姓名： | 于洋 张令志 黄洪志 姜诞宁 徐振武 汪伟业 秦洪义 刘潜心 |
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| 作者单位： | 第二军医大学第一附属医院传染科
(于洋，张令志，黄洪志，姜诞宁，徐振武，汪伟业)，第二军医大学病理科
(秦洪义)，第二军医大学病理科(刘潜心) |
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| 摘 要： | 本文报道了用D-氨基半乳糖诱发的急性肝坏死动物模型,早期应用胰高糖素、胰岛素、14氨基酸800注射液及东莨菪碱联合治疗。通过肝脏病理观察及~3H-胸腺嘧啶核苷体内掺入量的测定结果表明,胰高糖素-胰岛素等疗法,可抑制肝损害,并能促进肝细胞再生与修复。
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| 关 键 词： | 肝坏死 急性 胰高糖素-胰岛素 动物模型 大鼠 |
PRELIMINARY OBSERVATION ON THE EXPERIMENTAL TREATMENT FOR ACUTE HEPATIC NECROSIS WITH GLUCAGON AND INSULIN |
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| Yu Yang,et al.PRELIMINARY OBSERVATION ON THE EXPERIMENTAL TREATMENT FOR ACUTE HEPATIC NECROSIS WITH GLUCAGON AND INSULIN[J].Academic Journal of Second Military Medical University,1985(1). |
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| Authors: | Yu Yang |
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| Institution: | Yu Yang,et al Department of Infectious Diseases,First Teaching Hospital |
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| Abstract: | An experiment of treatment for acute hepatic necrosis with glucagon, insulin branched chain aminoacid and scopolamine in rats was reported.Liver specimens were investigated microscpically and a serial changes of 3H-TdR were evaluated.It is suggested that G-I therapy may reduce the hepatic injury and may also accelerate the regeneration of hepatic cells in D-gal-induced hepatic injiury.G-I thfrapy may be effective for prevention of progressing hepatic necrosis and promotion of hepatic regeneration in fulminant hepatic failure. |
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| Keywords: | hepatic necrosis acute glucagon-insulin rats animal model |
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