血浆置换治疗急性百草枯中毒24例临床分析

目的探讨血浆置换治疗急性百草枯中毒的治疗效果。方法2002年10月～2008年10月收治的24例急性百草枯中毒患者在原大剂量激素等综合治疗的基础上进行血浆置换,与未采用血浆置换治疗的18例急性百草枯中毒患者进行死因及死亡率对比。结果采用血浆置换治疗的24例急性百草枯中毒患者9例存活,存活率37.50%;死亡15例,死亡率62.50%;而未采用血浆置换治疗的18例急性百草枯中毒患者仅6例存活,存活率33.33%;死亡12例,死亡率66.67%。结论血浆置换治疗急性百草枯中毒有一定的效果,可延长生存期,但没有明显提高存活率。

Clinical analysis of plasam exchange to treat 24 patients associated with acute paraquat poisoning

Objective To investigate therapeutic effect of plasam exchange to treat acute paraquat poisioning. Methods 24 patients suffered with acute paraquat poisoning were treated by plasam exchange and heavy hormone and drugs from Oct.2002 to Oct. 2008.They were combined with 18 patients suffered with acute paraquat poisoning who weren＇t treated by plasam exchange in dead reasons and dead rates,respectively. Results 9 of 24 patients suffered with acute paraquat poisoning were conducted by plasam excharige and were cured ,and the rate of cure was 37.50%, 15 patients were dead and the dead rate was 62.50%. 18 patients suffered with acute paraquat poisoning weren＇t conducted by plasam exchange and only 6 of them were cured and the rate of cure was 33.33% ,12 of them were dead and the dead rate was 66.67%. Conclusions Plasam exchange bring some clinical effects in treatment of acute paraquat poisoning and make these patients＇ lives become longer,but it can＇t lower down these patients＇ mortality.