穴位贴敷法防治儿童支气管哮喘的队列研究

目的 评价穴位贴敷法防治儿童支气管哮喘的效果,分析可能影响其防治效果的因素。方法 以确诊的支气管哮喘患儿为研究对象,根据研究对象是否采用穴位贴敷治疗,将其分为贴敷组和未贴敷组。收集研究对象的基线资料后进行为期18个月的随访,获取病情变化积分。采用二项分类Logistic回归分析方法考察病情变化积分的影响因素。结果 329例哮喘患儿完成随访,其中贴敷组196例,未贴敷组133例。随访时间延长,患儿病情变化积分呈现逐渐降低趋势,贴敷组病情变化总积分低于未贴敷组,差异无统计学意义（P>0.05）。Logistic回归分析结果显示,仅贴敷年数进入病情变化积分的回归方程,贴敷年数越长,病情变化总积分越低。结论 基于“冬病夏治”理论的穴位贴敷法防治缓解期儿童支气管哮喘有一定的效果,贴敷时间长者的效果更明显。

Clinical Effect of Acupoint Sticking in Preventing and Treating Bronchial Asthma in Children: A Cohort Study

Objective To evaluate the clinical effect of acupoint sticking in preventing and treating bronchial asthma in children, and to analyze the potential influencing factors. Methods Children diagnosed with bronchial asthma were selected and divided into sticking group and non-sticking group according to whether they received acupoint sticking therapy. The baseline data of subjects were collected. Then, these patients were followed up for 18 months to obtain disease progression scores. A binary logistic regression analysis was used to determine the influencing factors for disease condition scores. Results A total of 329 children with asthma were followed up, consisting of 196 cases in the sticking group and 133 cases in the non-sticking group. The disease progression scores tended to decrease over the time of follow-up; the sticking group had an insignificantly lower total disease progression score than the non-sticking group (P>0.05). The logistic regression analysis showed that the total disease progression score decreased over the course of sticking therapy. Conclusion Acupoint sticking, which is based on the principle of "winter disease cured in summer", has a certain effect in preventing and treating pediatric asthma in remission stage, especially when used for a long period.