卒中后抑郁症中医证候虚实关联及演变规律研究

目的采用聚类分析的方法，研究卒中后抑郁症常见中医证候分布规律，进一步分析虚实证候关联及动态变化。方法设立54个常见卒中后抑郁症中医证候量表，分析常见症状，归纳为9个证候变量因子，进行聚类分析。结果9个证候变量因子中实证：肝气郁、痰浊证、瘀血证排在前三位，虚证：肝阴虚、肾阴虚、脾气虚、肾阳虚、脾阳虚、心气虚证候因子分别排在4—8位。证候虚实关联中肝郁气滞证、痰瘀交结证两个因子排在前两位，肝肾阴虚证、脾肾阳虚证、心脾两虚证3个证候因子分别排3—5位。结论各证候之间相互影响，相互演变，最终导致卒中后抑郁症缠绵难愈，严重影响卒中的康复。

Study on Relevance and Evolution of TCM Syndromes of Depression after Stroke

Objective to adopting the clustering analysis method, study on post stroke depression common distribution regularity of TCM Syndromes of excess syndromes, further analysis of correlation and dynamic change. Methods to set up 54 common TCM Syndromes of depression after stroke scale, analysis of common symptoms, divided into 9 syndromes of variable factors, clustering analysis. Results 9 syndrome variables empirical ： liver qi stagnation, phlegm, blood stasis in the top three, deficiency syndrome： deficiency of liver yin, kidney yin deficiency, spleen deficiency, kidney yang defi- ciency, spleen yang deficiency syndrome, heart qi deficiency syndrome factors were ranked in 4- 8. The two factor syn dromes and stagnation of liver qi stagnation syndrome association, phlegm stagnation syndrome in the top two, deficiency of two liver kidney yin deficiency, Yang deficiency of spleen and kidney, heart and spleen 3 syndrome factors were ranked 3 - 5. Among the syndromes Conclusion mutual influence, mutual development, eventually lead to post stroke depression lingering, serious impact on stroke rehabilitatiorL