| NP方案化疗治疗老年晚期非小细胞肺癌 |
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| 引用本文： | 蒋 葵,孙秀华,杨晓燕,张 弦,张 阳.NP方案化疗治疗老年晚期非小细胞肺癌[J].大连医科大学学报,2008,30(1):42-43+47. |
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| 作者姓名： | 蒋 葵 孙秀华 杨晓燕 张 弦 张 阳 |
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| 作者单位： | 大连医科大学,第二临床学院,肿瘤内科,辽宁,大连,116027 |
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| 摘 要： | 目的]评价NP方案治疗老年非小细胞肺癌疗效、毒性反应及其耐受性。方法]以国产长春瑞宾（NVB）联合顺铂（DDP）方案治疗老年晚期非小细胞肺癌（NSCLC）23例,NVB 25 mg/m^2静脉滴注,第1、8天;DDP 60mg/m^2,第1-3天静脉滴注,每21-28天重复,每周期观察其不良反应,每两周期评价疗效。结果]本组共完成化疗67个周期,中位周期数2个（2-6个）,总有效率26%,中位生存期10.3个月,1年生存率34.7%。最常见的毒性反应为白细胞减少,发生率为82.6%。胃肠道反应较轻。未见明显肝肾功能损害。结论]老年非小细胞肺癌患者对于NP方案耐受良好,毒性反应较轻,近期疗效令人满意。
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| 关 键 词： | 老年 非小细胞肺癌 化学治疗 |
| 文章编号： | 1671-7295（2008）01-0042-02 |
| 收稿时间： | 2007-08-31 |
| 修稿时间： | 2007-12-03 |
Vinorelbine and cisplatin regimein in treating elder patients with advanced non-small cell lung cancer |
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| JIANG Kui,SUN Xiu-hu,YANG Xiao-yan,ZHANG Xian and ZHANG Yang.Vinorelbine and cisplatin regimein in treating elder patients with advanced non-small cell lung cancer[J].Journal of Dalian Medical University,2008,30(1):42-43+47. |
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| Authors: | JIANG Kui SUN Xiu-hu YANG Xiao-yan ZHANG Xian and ZHANG Yang |
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| Institution: | Department of Oncology;the Second Affiliated Hospital of Dalian Medical University;Dalian 116027;China |
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| Abstract: | Objective] To estimate the efficacy,side-effects and tolerance of vinorelbine and cisplatin regimen in elder patients with advanced non-small cell lung cancer(NSCLC).Methods] Twenty three patients were treated by vinorelbine and cisplatin regimen.Vinorelbine were administered on day 1,8 introvenously with 25 mg/m2and cisplatin on day 1~3 with 60 mg/m2 every 3~4 weeks and at least 2 cycles.The efficacy and side effects were observed.Results] Sixty-seven cycles were completed totally.The overall response r... |
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| Keywords: | elder patients non- small cell lung cancer chemotheropy |
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