血清氨基酸和前白蛋白评估新生儿蛋白营养状况的临床应用价值

本实验通过对６６名不同胎龄新生儿，４０名患感染性疾病新生儿血清２０种游离氨基酸和前白蛋白的测定。实验表明：小于胎龄儿血中ＰＡ和部分ＦＡＡ较适于胎龄儿、大于胎龄儿显著降低；感染组新生儿血清中部分ＦＡＡ显著低于正常对照组，ＰＡ二组间无显著差异。

The clinical applyment value of assessing nutritional status of neonates by serum amino acid and prealbumin

In this study, the blood serum concentritions of 20 Free Amino Acid(FAA) and prealbumin(PA) were determined in 66 different gestational age of newborn and 40 newborn suffering from infectious disease. Our results indicated that small for gestational age(SGA) infants have significantly lower concentrations of PA and some FAA, compared with those of appropriate for gestational age(AGA) and large for gestational age(LGA) infants; Serum concentritions of some FAA in infectious newborn is lower than in normal newborn. No differences were observed between the infectious newborns and normal infants in PA. The values for Amino Acid ratios in SGA infants and infectious infants were similar to those found in protein-energy malnutrition. Our findings suggest blood serum PA and FAA might be used as sensitive markers to assess neonatal protein-energy malnutrition. Serum PA need to prudentially choosed in infectious disease because it will be affected by some other factors.