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胃粘膜上皮异型增生的临床病理学
引用本文:关宏伟,杜长春,张众.胃粘膜上皮异型增生的临床病理学[J].大连医科大学学报,1994(1).
作者姓名:关宏伟  杜长春  张众
作者单位:Department of Pathology,Dalian Medical College
摘    要:本文收集了132例胃粘膜上皮异型增生病例,分为腺瘤型、隐窝型和再生型;并分为轻、中、重三级及可疑癌,其中腺瘤型44例,隐窝型43例,再生型45例,轻度异型增生47例,中度异型增生49例,重度异型增生32例,可疑癌4例。通过临床病理资料复习,发现该病变高发年龄组为60岁年龄组,平均56.4岁,且随病变程度的加重,发病平均年龄增大,高发年龄组后移;患病男女比例为2.57:1;病变部位主要是胃窦部(占77.5%),胃底喷门少见。粘液组化染色发现随病变程度加重,细胞浆内粘液含量逐渐减少,在重度异型增生细胞浆内含量极少,主要位于近细胞游离缘处。

关 键 词:胃肿瘤,异型增生,腺瘤,再生

Clinic-pathology on epithelial dysplasia of gastric mucosa
Guan Hongwei, Du Changchun,Zhang Zhong.Clinic-pathology on epithelial dysplasia of gastric mucosa[J].Journal of Dalian Medical University,1994(1).
Authors:Guan Hongwei  Du Changchun  Zhang Zhong
Abstract:This paper collected 132 cases of gastric dysplasia. They can be divided into adenomatous type, cryptal type and regenerative type, and again divided into mild, moderate and severe grades and suspected cancer.The adenomatous type of dysplasia was 44 cases, cryptal type 43 cases,regenerative type 45 cases, mild grade 47 cases, moderate grade 49 cases,severe grade 32 cases and suspected cancer 4 cases. By review of clinical pathological data, it was found that the high peak of year group was that of 60s. The mean age was 56.4 years. The mean age will become higher, as the grade of the lesion become more severe, thus the high peak of age will shift to an older group. The ratio between male and female was 2.75:1. The lesion was mainly located in pyloric antrum(78.8%) and less common in cardia. Found by ABpH 2.5-PAS stainiing that, as the grade of lesion become more severe, the mucin content in cell plasm will corresponding decrease. The mucin cotent in cell plasm was rare in severe gastric dysplasia and mainly located in the free margin of the cell. This paper also investigated the background lesion in different types of gastric dysplasia and the practical value of mucin staining in typing and grading and their differential diagnosis. It was believed that these date had definite practical value.
Keywords:gastric tumor  dysplsia  adenoma  regeneration
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