| 山麦冬水溶性提取物亚急性毒性的实验观察 |
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| 引用本文： | 李淑媛,李卫平,周琴,李传勋,陈秀英,高广猷,张众,郑仁恕.山麦冬水溶性提取物亚急性毒性的实验观察[J].大连医科大学学报,1987(4). |
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| 作者姓名： | 李淑媛 李卫平 周琴 李传勋 陈秀英 高广猷 张众 郑仁恕 |
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| 作者单位： | 大连医学院药理教研室，大连医学院药理教研室，大连医学院药理教研室，大连医学院药理教研室，大连医学院药理教研室，大连医学院药理教研室，大连医学院病理教研室，大连医学院病理教研室 |
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| 摘 要： | 山麦冬水溶性提取物3g/kg、6g/kg、9g/kg给大鼠腹腔注射每天1次共2周,血尿素氮、GPT、Hb、Rbc、Wbc+Dc等指标均无明显改变。组织学检查表明,对其心、肝、脾、肺、肾未见明显毒性。
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| 关 键 词： | 山麦冬 亚急性毒性 组织学观察 |
THE SUBACUTE TOXICTY STUDIES OF WATER-SOLUBLE EXTRACT OF LIRIOPE SPICATA LOUR(WSEL) |
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| Li Shuyuan,et al.THE SUBACUTE TOXICTY STUDIES OF WATER-SOLUBLE EXTRACT OF LIRIOPE SPICATA LOUR(WSEL)[J].Journal of Dalian Medical University,1987(4). |
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| Authors: | Li Shuyuan |
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| Institution: | Li Shuyuan,et al Department of Pharmacology,Dalian Medical College |
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| Abstract: | In this paper,the subacute toxicity of WSEL on rats is reported. The results showed that through intraperitoneal injection of WSEL,in dosages of 3 g/kg, 6 g/kg and 9 g/kg respectively once daily to atotal time of two weeks, the values of blood urea nitrogen, GPT, Hb, Rbc and Wbc + DC did not show any significant change, and also, no significant toxic effects were found in the histological examination ofthe heart, the liver, the lung, the spleen and the kidney when compared with the control group. It is suggested that WSEL is a safe drug for clinical therapeutics. |
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| Keywords: | Liriope spicata lour Subacute toxicity Histologic examination |
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