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骨痹通天丸抗炎镇痛免疫作用研究
引用本文:肖顺汉,钱永龄.骨痹通天丸抗炎镇痛免疫作用研究[J].泸州医学院学报,1997,20(2):119-122.
作者姓名:肖顺汉  钱永龄
作者单位:泸州医学院药理学教研室!646000
摘    要:实验动物口服骨痹通天丸5.58g/kg.2.79g/kg,观察本品对炎症反应,局部疼痛和免疫功能的影响。结果表明,骨痹通天丸的两个剂量组对大鼠蛋清性关节肿具有不同程度的抑制作用(P<0.01或0.05);对二甲苯性耳廓肿仅大剂量组具有明显抑制作用(P<0.01);对小鼠热刺激所致的疼痛反应具有不同程度的抑制作用(P<0.01或0.05);对化学刺性疼痛两个剂量组均有明显抑制作用(P<0.01);并可抑制小鼠重要免疫器官的增长和巨噬细胞的吞噬功能(P<0.05),对血清溶血素未显示其效应。

关 键 词:骨痹通天丸  抗炎  镇痛  免疫作用  动物实验

STUDY ON ANTI-INFLAMMATION ANALGESIA AND LMMUNE EFFECTS OF GU BI TONG TIAN WAN
Xiao Shunhan,et al.STUDY ON ANTI-INFLAMMATION ANALGESIA AND LMMUNE EFFECTS OF GU BI TONG TIAN WAN[J].Journal of Luzhou Medical College,1997,20(2):119-122.
Authors:Xiao Shunhan  
Institution:Department of pharmacology. Luzhou Medical College
Abstract:Gu Bi Tong Tian Wan was fed to experimentol animals 5. 58g/kg/d. and 2. 79g/kg/d. respectzvely The effect of the drug on inflammation. Local analgesia and immune function wasobserved. The results showed that the drug inhibited the egema of paw induced by egg white in rats andswelling of ear in mice. Meanwhile, the drug prolonged heat-plate analgesia time in mice and significantly decrease twisty booly frequency in mice. Also, the weight of inportant immune organs andfunction of phagocytosis were decresed.
Keywords:Gu Bi Tong Tian Wan  Anti-inflammation  Analgesla  Lmmune effects  Experiments of animals
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