| 消瘤丸的体内抗瘤作用 |
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| 引用本文： | 刘秀书,郭鸣放,张永健,宋健徽,王川,许彦芳,梁国.消瘤丸的体内抗瘤作用[J].河北医科大学学报,1999,20(3):143-145. |
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| 作者姓名： | 刘秀书 郭鸣放 张永健 宋健徽 王川 许彦芳 梁国 |
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| 作者单位： | 河北医科大学基础医学院药理教研室,石家庄050017 |
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| 摘 要： | 探讨消瘤丸对小鼠移植性肿瘤的抑制和对环磷酰胺的增效作用。方法给小鼠腋下或腹腔接种肉瘤Ｓ１８０或肝癌Ｈ２２肿瘤细胞。结果消瘤丸对小鼠Ｓ１８０的生长有明显抑制作用，抑瘤率达２４％，并可显著增强环磷酰胺的抑瘤作用。
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| 关 键 词： | 抗肿瘤药 植物 秋水仙碱/分析 肿瘤 实验性 肿瘤/药物疗法 环磷酰胺/治疗应用 肿瘤/中医药疗法 小鼠 |
ANTITUMOR ACTIVITY OF XIAOLIUWAN PILL IN VIVO |
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| Liu Xiushu,Guo Mingfang,Zhang Yongjian,Song Jianhui,Wang Chuan,Xu Yanfang,Liang Guo.ANTITUMOR ACTIVITY OF XIAOLIUWAN PILL IN VIVO[J].Journal of Hebei Medical University,1999,20(3):143-145. |
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| Authors: | Liu Xiushu Guo Mingfang Zhang Yongjian Song Jianhui Wang Chuan Xu Yanfang Liang Guo |
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| Institution: | Shijiazhuang 050017 |
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| Abstract: | ObjectiveTo observe antitumor activity of Xiaoliuwan pill on tumorbearing mice.MethodsThe mice were transplanted by armpit or intraperitoneum injection of S 180 or H 22 tumor cells.ResultsXiaoliuwan pill(10 g/kg) inhibited markedly the growth of S 180 ( P < 0.01 ),with inhibitory rate of 24%,and enchanced the inhibitory effect of cyclophosphamide(5 mg/kg)on growth of S 180 ( P < 0.05 ),but the growth of H 22 and survival period of mice bearing H 22 insacites were not significantly affected by Xiaoliuwan pill ( P > 0.05 ).ConclusionXiaoliuwan pill can inhibit growth of S 180 tumor cell line,and has synergism with cyclophosphamide. |
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| Keywords: | antineoplastic agents phytogenic colchicine/anal neoplasms experimental neoplasms/drug ther cyclophosphamide/ther use neoplasms/TCM ther mice |
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