| 肝病患者血清甲状腺激素变化 |
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| 引用本文： | 赵彩彦,孙述强.肝病患者血清甲状腺激素变化[J].河北医科大学学报,1996,17(5):261-263. |
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| 作者姓名： | 赵彩彦 孙述强 |
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| 作者单位： | [1]附属三院传染科 [2]附属三院同位素科 |
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| 摘 要： | 测定１０９例不同肝病患者的血清甲状腺激素，与对照组比较，肝炎组Ｔ４、ｒＴ３、ｒＴ３／Ｔ３升高（Ｐ〈０．０５），Ｔ３／Ｔ４降低（Ｐ〈０．０１）。肝硬化组Ｔ３、Ｔ３／Ｔ４降低（Ｐ〈０．０１），ｒＴ３、ｒＴ３／Ｔ３升高（Ｐ〈０．０５），部分重症患者伴有Ｔ４降低。血清Ｔ３、Ｔ４与肝病患者血清胆红素、血浆白蛋白密切相关。血清Ｔ３含量尤其是Ｔ４浓度可预测肝病患者的预后，讨论了甲状腺激素浓度异常的发生机理和临床
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| 关 键 词： | 肝炎 肝硬化 甲状腺激素 血清 |
THYROID HORMONE CHANGES IN PATIENT WITH HEPATIC DISEASE |
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| Zhao Caiyan\ Cao Zhichen\ Zhen Zhen\ Liu Jinxing.THYROID HORMONE CHANGES IN PATIENT WITH HEPATIC DISEASE[J].Journal of Hebei Medical University,1996,17(5):261-263. |
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| Authors: | Zhao Caiyan\ Cao Zhichen\ Zhen Zhen\ Liu Jinxing |
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| Institution: | Zhao Caiyan\ Cao Zhichen\ Zhen Zhen\ Liu Jinxing Department of Infectious Disease,Third Affiliated Hospital Sun Shuqiang\ Liu Xiaomei Department of Isotope,Third Affiliated Hospital |
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| Abstract: | Serum thyroid hormones were determined in 109 patients with hepatic disease. The results were compared with controls. T 4, rT 3 and ratio of rT 3/T 3 were significantly increased (P<0.05),but the ratio of T 3/T 4 was decreased significantly (P< 0.01) in patients with hepatitis. In patients with liver cirrhosis, the serum concentrations of T 3 and ratio of T 3/T 4 were lower (P<0.01),while rT 3 and ratio of rT 3/T 3 were higher (P< 0.05). Low level of serum T 4 was found in some severe cases with liver cirrhosis. The serum concentrations of T 3, T 4 correlated closely with that of bilirubin and albumin. Serum concentration of T 3, especially T 4 could indicated the prognosis of patients with hepatic disease. The mechanism of thyroid hormone changes and clinical significance were discussed. |
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| Keywords: | hepatitis liver cirrhosis thyroid hormone |
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