| 龈沟液中HGF及IL-1β含量与牙周炎关系的研究 |
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| 引用本文： | 刘丽英,赵满琳,崔占琴,马永平,柴勇.龈沟液中HGF及IL-1β含量与牙周炎关系的研究[J].河北医科大学学报,2006,27(3):185-187. |
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| 作者姓名： | 刘丽英 赵满琳 崔占琴 马永平 柴勇 |
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| 作者单位： | 1. 保定市第二医院口腔科,河北,保定,071051
2. 河北医科大学第二医院口腔科,河北,石家庄,050000 |
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| 摘 要： | 目的分析龈沟液(gingival crevicular fluid,GCF)中肝细胞生长因子(hepatocyte growth factor,HGF)和白细胞介素-1β(interleukin-1 beta,IL-1β)的含量变化规律及其与牙周炎的关系.方法采用酶联免疫吸附(enzyme-1inked immunosorbent assay,ELISA)试验对健康人以及慢性牙周炎患者牙周基础治疗前后龈沟液中HGF和IL-1β的含量进行检测.结果HGF总量及IL-1β总量在治疗前牙周炎位点明显高于健康位点,差异有显著性意义(P＜0.01).经牙周治疗后,HGF总量及IL-1β总量均明显减少,且差异有显著性意义(P＜0.01).HGF总量和IL-1β总量呈明显相关关系.结论龈沟液中HGF与IL-1β水平与牙周炎症程度密切相关.龈沟液中HGF与IL-1β水平可作为反映牙周状况的有利指标.
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| 关 键 词： | 牙周炎 龈沟液 肝细胞生长因子 白细胞介素1 |
| 文章编号： | 1007-3205(2006)03-0185-03 |
| 收稿时间： | 2006-01-25 |
| 修稿时间： | 2006-02-26 |
RELATIONSHIP BETWEEN PERIODONTITIS AND CONTENT OF HGF AND IL-1β IN GINGIVAL CREVICULAR FLUID |
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| LIU Li-ying,ZHAO Man-lin,CUI Zhan-qin,MA Yong-ping,CHAI Yong.RELATIONSHIP BETWEEN PERIODONTITIS AND CONTENT OF HGF AND IL-1β IN GINGIVAL CREVICULAR FLUID[J].Journal of Hebei Medical University,2006,27(3):185-187. |
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| Authors: | LIU Li-ying ZHAO Man-lin CUI Zhan-qin MA Yong-ping CHAI Yong |
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| Institution: | 1. Department of Stomatology ,the Second Hospital of Baoding City, Baoding 071051 ,China ;2. Department of Stomatology , the Second Hospital of Hebei Medical University, Shijiazhuang 050000 ,China |
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| Abstract: | |
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| Keywords: | periodontitis gingival crevicular fluid hepatocyte growth factor interleukin-1 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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