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补充肉毒碱治疗少弱精子症疗效观察
引用本文:李铮,谷荣华,刘勇,向祖琼,曹小蓉,韩银发,张贤生,王益鑫.补充肉毒碱治疗少弱精子症疗效观察[J].上海交通大学学报(医学版),2005,25(3):292-294.
作者姓名:李铮  谷荣华  刘勇  向祖琼  曹小蓉  韩银发  张贤生  王益鑫
作者单位:上海第二医科大学仁济医院上海市男科学研究所 上海200001 (李铮,谷荣华,刘勇,向祖琼,曹小蓉,韩银发,张贤生),上海第二医科大学仁济医院上海市男科学研究所 上海200001(王益鑫)
摘    要:目的探讨补充肉毒碱治疗少弱精子症的疗效与安全性。方法80例不育症患者随机分为治疗组与对照组各40例,治疗组口服肉毒碱口服液,对照组服用VitC与VitE,治疗3月后评定疗效。结果口服肉毒碱的治疗组有效率为82.25%,精浆肉毒碱浓度有明显增高,与对照组比较有显著性差异(P<0.01)。结论口服补充肉毒碱治疗少弱精子症疗效显著,无严重不良反应。

关 键 词:治疗组  少弱精子症  肉毒碱  对照组  口服  疗效  补充  显著性差异  有效率  精浆
文章编号:0258-5898(2005)03-0292-03
修稿时间:2004年3月17日

Curative Effect of L-carnitine Supplementation in the Treatment of Male Infertility
LI Zheng,GU Rong-hua,LIU Yong,XIANG Zu-qiong,CAO Xiao-rong,HAN Yin-fa,ZHANG Xian-sheng,WANG Yi-xin.Curative Effect of L-carnitine Supplementation in the Treatment of Male Infertility[J].Journal of Shanghai Jiaotong University:Medical Science,2005,25(3):292-294.
Authors:LI Zheng  GU Rong-hua  LIU Yong  XIANG Zu-qiong  CAO Xiao-rong  HAN Yin-fa  ZHANG Xian-sheng  WANG Yi-xin
Abstract:Objective To explore the effectiveness and safety of L-carnitine supplement in the treatment of male infertility. Methods Eighty patients with infertility were divided in two groups, 40 treatment group and 40 control group. The patients in treatment group took the L-canitine liquid, 2 g daily, while those controls took Vit C and Vit E. The results were evaluated after 3 months. Results The effective rate was 82.25% ,and seminal L-carnitine concentration and total carnitine increased in treatment group. Compared with controls, the difference was statistically significant. Conclusion The L-carnitine supplement to treat male infertility is effective and safe.
Keywords:L-carnitine  male infertility  asthenozoospermia
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