| 代谢组学在恶性肿瘤中的应用 |
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| 引用本文： | 樊 星,综述,李军民,陈赛娟,审校.代谢组学在恶性肿瘤中的应用[J].上海交通大学学报(医学版),2009,29(10):1246. |
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| 作者姓名： | 樊 星 综述 李军民 陈赛娟 审校 |
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| 作者单位： | 上海交通大学,医学院瑞金医院,上海血液学研究所,上海,200025 |
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| 摘 要： | 代谢组学是系统生物学的分支之一,应用核磁共振和质谱等技术检测各种体液的代谢物变化,研究各种代谢物分子及其功能,有助于发现相关疾病发生早期的代谢组标志物簇,深入理解相关病理发生的分子机制,为恶性肿瘤的早期诊断及个体化治疗等方面提供广阔的应用前景.
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| 关 键 词： | 代谢组学 恶性肿瘤 早期诊断 分子标记物 个体化治疗 |
Application of metabolomics in malignant tumors |
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| FAN Xing,reviewer,LI Jun-min,CHEN Sai-juan,reviser.Application of metabolomics in malignant tumors[J].Journal of Shanghai Jiaotong University:Medical Science,2009,29(10):1246. |
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| Authors: | FAN Xing reviewer LI Jun-min CHEN Sai-juan reviser |
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| Institution: | Shanghai Institute of Hematology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China |
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| Abstract: | Metabolomics is one of the branches of systems biology, which employs nuclear magnetic resonance and mass spectrometry technologies to detect the abnormal metabolites from a variety of body fluids. Study of various molecules and their functions may help to find the disease-related early metabolic marker clusters, understand the molecular mechanism of pathogenesis, which provides broad prospects for the early diagnosis and individualized treatment of malignant tumors. |
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| Keywords: | metabolomics malignant tumor early diagnosis biomaker individualized treatment |
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