| 慢性疼痛动物模型的研究进展 |
| |
| 引用本文： | 周秋雯,徐建国.慢性疼痛动物模型的研究进展[J].医学研究生学报,2008,21(6):638-642. |
| |
| 作者姓名： | 周秋雯 徐建国 |
| |
| 作者单位： | 南京军区南京总医院,南京大学医学院临床学院,麻醉科,江苏南京210002 |
| |
| 摘 要： | 神经病理性疼痛及癌性疼痛为临床上最为常见、最难治疗的两种慢性疼痛。为研究慢性疼痛发病机制和探索新的治疗方法,目前已制作出许多动物模型。文章介绍了中枢性损伤、周围神经损伤以及疾病所致周围神经病变和癌性疼痛等常见动物模型及其特征。
|
| 关 键 词： | 慢性疼痛 神经病理性疼痛 癌痛 痛觉异常 痛觉过敏 动物模型 |
Animal models of chronic pain |
| |
| ZHOU Qiu-wen,XU Jian-guo.Animal models of chronic pain[J].Bulletin of Medical Postgraduate,2008,21(6):638-642. |
| |
| Authors: | ZHOU Qiu-wen XU Jian-guo |
| |
| Abstract: | Neuropathic pain and cancer pain are two difficult types of chronic pain to be controlled by currently available analgesics.Animal models can provide pivotal systems for preclinical study of pain.This article reviews some new models of chronic pain,such as those of cancer pain,central nerve pain,and the pain caused by peripheral nerve injury and disease-induced peripheral neuropathy. |
| |
| Keywords: | Chronic pain Neuropathic pain Cancer pain Allodynia Hyperalgesia Animal model |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
