| 新的冠心病预测标记—心外膜脂肪 |
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| 引用本文： | 王璟,吴宗贵,江时森.新的冠心病预测标记—心外膜脂肪[J].医学研究生学报,2008,21(9). |
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| 作者姓名： | 王璟 吴宗贵 江时森 |
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| 作者单位： | 1. 第二军医大学南京临床医学院,南京军区南京总医院心血管内科,江苏南京,210002
2. 第二军医大学附属长征医院心内科,上海,200003 |
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| 摘 要： | 内脏脂肪组织增加已被公认是动脉粥样硬化性疾病和代谢综合征的一个重要危险因素,对内脏脂肪组织的鉴别和评价是至关重要的.心外膜脂肪是沉积在心脏周同真正的脂肪组织,特别是围绕在冠状动脉周围.心外膜脂肪组织可表达多种与动脉粥样硬化相关的细胞因子和蛋白,与冠状动脉粥样硬化的发展密切相关.因心外膜脂肪组织特殊的解剖位置和生理生化特性,故可将其作为一个新的冠心病预测标记和代谢综合征潜在的治疗靶点.
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| 关 键 词： | 心外膜脂肪组织 内脏脂肪 炎症 动脉粥样硬化 冠状动脉疾病 |
Epicardial adipose tissue: a new marker of coronary heart disease |
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| WANG Jing,WU Zong-gui,JIANG Shi-sen.Epicardial adipose tissue: a new marker of coronary heart disease[J].Bulletin of Medical Postgraduate,2008,21(9). |
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| Authors: | WANG Jing WU Zong-gui JIANG Shi-sen |
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| Institution: | WANG Jing1 reviewing,WU Zong-gui2,JIANG Shi-sen1 checking(1.Department of Cardiology,Nanjing School of Clinical Medicine,the Second Military Medical University / Nanjing General Hospital of Nanjing Military Comm,,PLA,Nanjing 210002,Jiangsu,China,2.Department of Cardiology,Changzheng Hospital,the Second Military Medical University,Shanghai 200003,China) |
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| Abstract: | Epicardial adipose tissue is true visceral fat deposited around the heart,particularly around subepicardial coronary vessels.While little is known about the pathophysiologic and metabolic roles of epicardial fat.Epicardial adipose tissue expresses numerous genes for cytokines and proteins associated with atherosclerosis.Epicardial adipose tissue may serve as a new predictive marker of coronary heart disease and potential therapeutic target in the metabolic syndrome. |
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| Keywords: | Epicardial adipose tissue Visceral fat Inflammation Atherosclerosis Coronary disease |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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