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兔肾VX2肿瘤的超声造影实验研究
引用本文:沈德娟,杨斌,倪黎登,傅宁华,王江陵.兔肾VX2肿瘤的超声造影实验研究[J].医学研究生学报,2008,21(5):491-494.
作者姓名:沈德娟  杨斌  倪黎登  傅宁华  王江陵
作者单位:1. 南京大学医学院临床学院(南京军区南京总医院)超声诊断科,江苏南京,210002
2. 南京大学医学院临床学院(南京军区南京总医院)普通外科,江苏南京,210002
基金项目:南京军区南京总医院科研基金重点项目
摘    要:目的:探讨兔VX2肾肿瘤超声造影的图像特征。方法:12只新西兰兔采用包埋法于右肾植入VX2肿瘤,共12个结节。经外周静脉注射声诺维(SonoVue),分别于植瘤后7、14、21 d进行超声造影,观察VX2肿瘤大小及其灌注特点。结果:肿瘤最佳干预时间为植入后2~3周,3周后易发生坏死。VX2肾肿瘤超声造影后主要表现为充盈缺损的"负显影",可使肾肿瘤的检出率由造影前的57.1%(12/21)提高至造影后的100%(21/21)。结论:超声造影可明显加强肿瘤血流信号的显示,显著提高VX2肾肿瘤的诊断率。

关 键 词:超声造影  肾肿瘤  VX2
文章编号:1008-8199(2008)05-0491-03
修稿时间:2007年8月15日

Contrast-enhanced ultrasonography improves diagnosis of renal VX2 tumor in rabbits
SHEN De-juan,YANG Bin,NI Li-deng,FU Ning-hua,WANG Jiang-ling.Contrast-enhanced ultrasonography improves diagnosis of renal VX2 tumor in rabbits[J].Bulletin of Medical Postgraduate,2008,21(5):491-494.
Authors:SHEN De-juan  YANG Bin  NI Li-deng  FU Ning-hua  WANG Jiang-ling
Abstract:Objective:To evaluate the characteristics of contrast-enhanced ultrasonography in renal VX2 tumors.Methods: VX2 tumors were transplanted into 12 rabbit kidneys and observations were made by contrast-enhanced ultrasonography 7,14 and 21 days after the transplantation respectively.Results: The best intervention time was 2-3 weeks after the tumor transplantation,while nicrosis was apt to occur after 3 weeks.The visibility of the renal tumors was significantly increased from 57.1%(12/21) to 100%(21/21).Contrast-enhanced ultrasonography showed defect and delineation of VX2 tumors. Conclusion: Contrast-enhanced ultrasonography can improve the peripheral and internal blood flows of the tumors promote the diagnosis of renal tumors.
Keywords:Contrast-enhanced ultrasonography  Renal tumor  VX2
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