| 加强动物实验建设,为科研工作提供良好的支撑条件 |
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| 引用本文： | 孙荣国.加强动物实验建设,为科研工作提供良好的支撑条件[J].实验动物与比较医学,2003,23(4):243-244. |
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| 作者姓名： | 孙荣国 |
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| 作者单位： | 四川大学医学管理处,成都,610041 |
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| 基金项目： | 广东省中医药管理局资金资助(101106) |
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| 摘 要： | 实验动物是科研的工作的重要支撑条件之一。本文从四个方面探讨了在新世纪加强动物实验建设，为科研工作提供良好的支撑条件的原则和措施。
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| 关 键 词： | 动物实验 科研工作 支撑条件 基地建设 |
| 文章编号： | 1004-8448(2003)04-0243-02 |
| 修稿时间： | 2003年4月14日 |
Procyanidine Therapy for ARDS Model in Rat |
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| XIE Yang_min,LIN Chu_ling,LIN Jue_long,CHEN Han_qiu,LI Mei.Procyanidine Therapy for ARDS Model in Rat[J].Laboratory Animal and Comparative Medicine,2003,23(4):243-244. |
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| Authors: | XIE Yang_min LIN Chu_ling LIN Jue_long CHEN Han_qiu LI Mei |
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| Abstract: | To detect the liver spontaneous lesions of beagle dogs used in toxicity studies. Sixty beagle dogs from control experimental groups, age from 10-18 months were used. Liver fune-tion index of serum were tested and liver samples were observed by routine histological tech-nique. The results revealed that all 7 clinical index were deviated in different degree. Various spontaneous lesions amounting to 20 kinds in different degrees were found in 63. 3% dogs of the study, ineluding hepatocyte degenerations, necroses,and proliferations, connective fiber proliferations and fibrosis ,inflammatory cell infiltration ,abscess and cystis. The degree and the frequen cy of lesions was no difference between the sex. Usually several kinds of lesions occurred in the liver of one dog. It is suggested that spontaneous lesions should be monitored so as to provide histopathological investigations for safety estimation experiment of new medicine. |
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| Keywords: | Respiratory Distress Syndrome Procyanidolic Treatment Outcome |
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