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基于MRI测量正常成人半月板厚度的形态学研究
作者姓名:潘斯学  何光雄  夏吉良  陈帅  向俊宜  保超宇
作者单位:1.云南中医药大学第一临床医学院,云南 昆明 650500
基金项目:云南省科技计划基金资助项目(11372110236,2018NS0037)
摘    要:  目的  采用MRI扫描成像技术测量正常成人膝关节内外侧间室半月板前后角的厚度,为全膝关节置换假体设计和优化人工半月板设计提供技术手段、参数。  方法  随机抽取 2020年01月至 2022年06月在云南省中医医院就诊的成年患者行单侧膝关节MRI扫描成像的影像学资料,MRI片示无膝关节水肿、半月板明显退变、半月板损伤及撕裂等的248例影像资料作为样本,其中女性137例,男性111例,年龄18~80岁,中位年龄50岁。观察膝关节的矢状面MRI片。由3名资深临床医师测量膝关节内侧间室的半月板前后角厚度、膝关节外侧间室的半月板前后角厚度,并取3次测量结果的平均值作为最终测量结果。测量结果采用SPSS27.0统计学软件包进行统计学分析。  结果  内侧间室半月板前角厚度为(3.65±0.93)mm;内侧间室半月板后角厚度为(5.25±1.17)mm;外侧间室半月板前角厚度为(4.82±1.08)mm;外侧间半月板后角厚度为(6.89±1.03)mm;经两独立样本t检验,男女内侧间室半月板后角厚度,差异有统计学意义(P < 0.05);左右侧膝关节内侧间室半月板前后角厚度和外侧间室半月板前角厚度,差异具有统计学意义(P < 0.05);经Pearson相关性分析,男女性内侧间室半月板前角厚度和内侧间室半月板后角厚度均具有相关性(P < 0.05);男女性外侧间室半月板前角厚度和外侧间室半月板后角厚度均具有相关性(P < 0.05)。  结论  利用MRI成像技术,通过对半月板形态的测量揭示了正常成人半月板形态学的特点及变化规律,有利于全膝关节置换假体设计和优化人工半月板设计,从而更好的指导临床治疗。

关 键 词:磁共振成像    成年人    半月板    厚度    形态学研究
收稿时间:2022-06-29

Morphological Study of Meniscus Thickness Measurement in Normal Adults Based on MRI
Institution:1.The 1st School of Clinical Medicine,Yunnan University of Traditional Chinese Medicine,Kunming Yunnan 650500)2.Dept. of Orthopedics,The 1st Affiliated Hospital of Yunnan University of Traditional Chinese Medicine/Yunnan Hospital of Traditional Chinese Medicine, Kunming Yunnan 650021,China
Abstract:  Objective  MRI scanning technique was used to measure the thickness of the anterior and posterior angles of the medial and lateral compartments of the knee joint in normal adults, so as to provide technical means and parameters for the design of total knee replacement prosthesis and the optimization of artificial meniscus design.   Methods  The imaging data of MRI scanning of unilateral knee joint of adult patients in Yunnan Traditional Chinese medicine hospital from January 2020 to June 2022 were randomly selected. 248 cases without knee edema, obvious degeneration of meniscus, meniscus injury and tear in MRI films were taken as samples, including 137 women, 111 men, 18-80 years old, with a median age of 50 years. The sagittal MRI films of knee joint were observed, Three senior clinicians measured the meniscus anterior and posterior angle thickness of the medial compartment of the knee joint and the meniscus anterior and posterior angle thickness of the lateral compartment of the knee joint, and the average of the three measurements was taken as the final measurement result. The measurement results were statistically analyzed by spss27.0 statistical software package.   Results  The thickness of anterior horn of meniscus in the medial compartment was (3.65 ± 0.93)mm; the thickness of posterior horn of meniscus in the medial compartment was (5.25 ± 1.17)mm; the thickness of anterior horn of meniscus in the lateral compartment was (4.82 ± 1.08)mm; the thickness of posterior horn of lateral in the lateral compartmentwas (6.89 ± 1.03)mm. The t test of two independent samples showed that the thickness of the posterior angle of meniscus in the medial compartment was statistically significant between men and women (P < 0.05). The anterior and posterior Angle thickness of the meniscus in the medial ventricle of the left and right knee joints was significantly different from that in the lateral ventricle (P < 0.05). According to Pearson correlation analysis, there was a correlation between the anterior angle thickness of medial interventricular meniscus and the posterior angle thickness of medial interventricular meniscus in both sexes (P < 0.05). There was a correlation between the thickness of anterior horn of lateral interventricular meniscus and the thickness of posterior horn of lateral interventricular meniscus in both sexes (P < 0.05).  Conclusion  In this study, MRI imaging technology was used to reveal the morphological characteristics and changes of meniscus in normal adults through the measurement of meniscus morphology, which is conducive to the design of total knee replacement prosthesis and the optimization of artificial meniscus design, so as to better guide clinical treatment.
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