艾滋病合并恶性肿瘤10例临床病理分析

目的:分析艾滋病(AIDS)合并恶性肿瘤的临床与病理特点。方法:对会诊和复查的48例AIDS患者的病理活检与尸检材料进行临床、影像、解剖与病理对照研究。结果:48例AIDS患者中合并恶性肿瘤10例;其中儿童2例系母婴传播;成年人8例中经输血传播4例。合并非霍奇金淋巴瘤4例,乳腺癌2例,卡波西肉瘤1例,肝母细胞瘤1例,食管癌1例,肾癌1例。结论:AIDS患者易合并恶性肿瘤,疾病谱广泛,以淋巴瘤多见,确诊需依赖病理检查。

Clinicopathological analysis of ten cases of acquired immunodeficiency syndrome patients complicated with malignant tumors

Objective:To analyze the clinicopathological characteristics of acquired immunodeficiency syndrome ( AIDS ) patients complicated with malignant tumors. Methods:The consulted pathological biopsy and autopsy data of 48 AIDS patients were studied by the combination of clinical analysis,imaging,anatomy and pathology. Results:Among the 48 AIDS cases,10 patients were complicated with malignant tumors;the 2 children acquired the disease from their mothers and 4 of the 8 adults from blood transfusion. Four of the cases were complicated with non-Hodgkin lymphoma,2 cases breast carcinoma,1 case was complicated with Kaposi's sarcoma,1 case hepatic blastoma,1 case esophageal carcinoma and 1 case renal carcinoma. Conclusions:AIDS patients tend to develop malignant tumors with broad spectrum,among which malignant lymphoma and Kaposi's sarcoma are commonly seen. Diagnosis should be based on pathologic examination.