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脑膜癌病2例报道及文献复习
引用本文:刘艳,陈卓,易建中,赵德明.脑膜癌病2例报道及文献复习[J].蚌埠医学院学报,2009,34(3):225-227.
作者姓名:刘艳  陈卓  易建中  赵德明
作者单位:安徽省淮北市人民医院,神经内科,235000;安徽省濉溪县人民医院,神经内科,235100
摘    要:目的:探讨脑膜癌病的临床及脑脊液细胞学特征。方法:总结2例脑膜癌病的临床及脑脊液细胞学特征,并复习文献。结果:1例为慢性粒细胞白血病急性变,1例为乳腺癌术后;临床主要表现头痛、呕吐,无脊神经损害及脑膜刺激征。脑脊液检查颅内压增高,细胞数、蛋白升高,细胞学检查发现癌细胞。结论:脑脊液细胞学检查是诊断脑膜癌病的重要依据。

关 键 词:脑膜肿瘤  脑膜癌病  脑脊髓液/分析  细胞诊断学

Meningeal carcinomatasis:report of 2 cases and review of the literature
LIU Yan,CHEN Zhuo,YI Jian-zhong,ZHAO De-ming.Meningeal carcinomatasis:report of 2 cases and review of the literature[J].Journal of Bengbu Medical College,2009,34(3):225-227.
Authors:LIU Yan  CHEN Zhuo  YI Jian-zhong  ZHAO De-ming
Institution:LIU Yan , CHEN Zhuo , YI Jian-zhong, ZHAO De-ming (1. Department of Neurology , Huaibei People's Hospital , Huaibei Anhui 235000; 2. Department of Neurology, Suixi County People's Hospital, Suixi Anhui 235100, China )
Abstract:Objective: To explore the clinical features and cytological changes of cerebrospinal fluid (CSF) in meningeal carcinomatasis. Methods : The clinical features and cytological changes of CSF of two meningeal carcinomatasis patients were analyzed, and the literature was reviewed. Results: Of the two cases of meningeal carcinomatasis, one was due to acute change of chronic myelocytic leukemia and the other had received surgery for breast cancer. The main clinical manifestations were headache and vomiting. No spinal nervous lesion or signs of meningeal irritation were observed. Abnormal level of intracranial pressure, increased cell count and protein level were found in CSF examination. Cancer cells were found in cytological examination Conclusions: The cytological examination of CSF is essential for the diagnosis of meningeal carcinomatasis.
Keywords:meningeal neoplasms  meningeal carcinomatasis  cerebrospinal fluid/analysis  cytodiagnosis
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