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生物粘合剂预防胆道狭窄的实验观察
引用本文:张莉,郭善禹.生物粘合剂预防胆道狭窄的实验观察[J].蚌埠医学院学报,1998,23(5):303-304.
作者姓名:张莉  郭善禹
作者单位:附属医院整形外科
摘    要:明确生物粘合剂取代 缝线重建胆道,能否预防吻合口狭窄。方法将54只杂种犬随机为A、B、C三组。

关 键 词:瘢痕  胶原含量  胆道狭窄  预防  生物粘合剂

Use of fibrin glue in choledochojejunostomy for prevention of stricture
Zhang Li,Guo Shanyu,Zhou Linbin,Sun Jianmin,Yao Decheng.Use of fibrin glue in choledochojejunostomy for prevention of stricture[J].Journal of Bengbu Medical College,1998,23(5):303-304.
Authors:Zhang Li  Guo Shanyu  Zhou Linbin  Sun Jianmin  Yao Decheng
Abstract:Objective:To determine the result of using fibrin glue(FG) instead of conventional suture in experimental bile duct reconstruction for preventing anastomotic stricture.Methods:54 dogs were divided at random into 3 groups.Group A( n =18),choledochojejunostomy was made with FG for anastomosis;in group B( n =18),choledochojejunostomy with FG for anastomosis,together with an indwelling stent;in group C( n =18),the indwelling stent was removed after a definite time.The anastomotic scar tissues were taken for examination of biochemical collogen content(BCC) at 3 weeks,3 months,6 months,9 months and 12 months after operation.Results:BCC in group A showed no significant difference 9 months after operation.BCC in group B and group C showed no significant difference 6 months after operation.Conclusions:FG has the advantages in promoting wound healing,limiting scar formation and accelerating scar maturation.Together with indwelling stent is an effective measure in preventing anastomosis stenosis.
Keywords:biocompatible materials  biliary tract diseases  choledochojejunostomy  cicatrix  collaogen
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