妊娠合并血小板减少围产结局分析

目的 探讨妊娠合并血小板减少的病因、临床表现、对孕妇及新生儿的影响、分娩方式、麻醉方式等.方法 回顾性分析107例妊娠合并血小板减少患者的临床资料,按照血小板计数水平将观察组患者分为3组进行比较.结果 PAT是以轻度血小板减少为主（76.47％）,各类病因间不同血小板减少程度构成比差异有统计学意义（P＜0.05）;重度和中度血小板减少组的剖宫产率与正常对照组比较差异有显著性（P＜0.05）;各组间比较麻醉方式有显著性差异（P＜0.05）;在新生儿体重方面,重度组与正常组差异有显著性（P＜0.05）,各组间1 min阿氏评分无显著差异,胎儿宫内窘迫在重度组与轻度组、对照组之间比较差异有显著性（P＜0.05）,死胎发生例数各组间差异不明显.结论 血小板减少程度的高低对于患者的分娩方式、剖宫产率、新生儿出生指标、围产儿死亡等各方面均有不同影响.

The Analysis of Outcome of Thrombocytopenia in Pregnancy Abstract

Objective The aim of this study is to investigate the cause, Clinical manifestations, impact on pregnant women and newborns, mode of delivery, anesthesia methods, etc. Methods To retrospectively analy- sis the clinical data of 107 patients of pregnant women with thrombocytopenia. The observation group were di- vided into three groups in accordance with the level of platelet counts. Results PAT is mainly mild thrombocy- topenia （76.47 % ）. In the ratio of platelet minimize, the difference among all types of causes was significant. The difference of cesarean rate between severe thrombocytopenia group or moderate thrombocytopenia group and normal control group was significant（P 〈 0.05）. The conclusion of comparing the application of anesthesia in all groups is that they have significant difference（P 〈 0.05）. Difference of neonatal weight between severe throm- bocytopenia group and the normal group was significant（P 〈 0.05） ;Among all groups, there are no significant difference in 1 - minute Apgar score. The difference of fetal distress between severe thrombocytopenia group and mild thrombocytopenia group or normal control group is significantly different（ P 〈 0.05 ）. Stillbirth among all groups is not significantly different. Conclusion Degree of thrombocytopenia in patients all have different im- pacts on the mode of delivery, cesarean section rate, birth indicators, perinatal death.