重症监护病房鲍曼不动杆菌和铜绿假单胞菌的分布及耐药性研究

目的探讨重症监护病房（ICU）鲍曼不动杆菌以及铜绿假单胞菌的分布情况以及耐药性。方法收集2012年1月-2014年1月,我院ICU感染患者的送检标本160份,鉴定感染菌株种类,并对鲍曼不动杆菌以及铜绿假单胞菌进行耐药性分析。结果 ICU鲍曼不动杆菌以及铜绿假单胞菌均存在不同程度的耐药性,其中,鲍曼不动杆菌对于亚胺培南敏感性最高（88.0%）,其次为头孢哌酮/舒巴坦（81.3%）,其余均在70%以下；铜绿假单胞菌对亚胺培南以及头孢他啶的敏感性最高,均为82.4%,其次为头孢哌酮/舒巴坦（81.2%）。结论 ICU鲍曼不动杆菌以及铜绿假单胞菌均存在严重抗菌药物耐药性,强化ICU耐药监测对于预防医院感染的发生和流行具有重要意义。

The Research of Distribution and Drug Resistance of Bauman Acinetobacter and Pseudomonas Aeruginosa of ICU

Objective To study the research of distribution and drug resistance of Bauman Acinetobacter and Pseudomonas Aeruginosa of ICU.Method We collected 160 infection specimens of patients with ICU in our hospital（from January 2012 to 2014）,identified the types of infecting strains and analyzed the drug resistance of Bauman Acinetobacter and Pseudomonas Aeruginosa.Result： the Bauman Acinetobacter＇s susceptibility to imipenem was the highest（88%）,followed by Cefoperazone/Shubatan（81.3%）and the rest were below 70%.Pseudomonas Aeruginosa＇s susceptibility to imipenem and ceftazidime was the highest（82.4%）,followed by Cefoperazone/sulbactam（81.2%）.Conclusion The Bauman Acinetobacter and Pseudomonas Aeruginosa of ICU have high drug resistance.It is important for strengthening the ICU monitoring of drug resistance to prevent severe nosocomial infection.