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3.0T MRS与FATSAT对胰腺脂肪含量定量分析的可行性研究
引用本文:袁放,宋彬,唐鹤菡,陈光文,李静,谢屹.3.0T MRS与FATSAT对胰腺脂肪含量定量分析的可行性研究[J].四川大学学报(医学版),2010,41(1).
作者姓名:袁放  宋彬  唐鹤菡  陈光文  李静  谢屹
作者单位:1. 四川大学华西医院,放射科,成都,610041
2. 四川大学华西医院,消化内科,成都,610041
摘    要:目的 探讨3.0T磁共振波谱测量技术(MR spectroscopy,MRS)与频率选择脂肪预饱和技术(fat saturation,FATSAT)对胰腺脂肪含量定量分析的可行性.方法 对35例健康志愿者胰腺行双回波同去相位磁共振成像(in-phase and out-of-phase,IP/OP),MRS、FATSAT序列扫描,测量胰腺脂肪含量(fat content,FC),以IP/OP法测得值为标准进行相关性分析.结果 IP/OP、FATSAT及MRS 3种方法 测得35例志愿者胰腺平均脂肪含量分别为(8.2±2.0)%、(11.8±4.7)%及(8.8±4.6)%,MRS与IP/OP之间呈正相关(r=0.809,P<0.001),FATSAT与IP/OP之间无相关性(r=0.311,P=0.069).结论 在3.0T磁共振成像系统下,MRS对于胰腺脂肪的定量分析是可行的,而FATSAT不适用于胰腺脂肪的定量分析.

关 键 词:磁共振波谱  双回波同去相位  脂肪预饱和  胰腺  脂肪含量

Quantification of Pancreas Fat by MRS and FATSAT with 3.OT MRI
YUAN Fang,SONG Bin,TANG He-han,CHEN Guang-wen,LI Jing,XIE Yi.Quantification of Pancreas Fat by MRS and FATSAT with 3.OT MRI[J].Journal of West China University of Medical Sciences,2010,41(1).
Authors:YUAN Fang  SONG Bin  TANG He-han  CHEN Guang-wen  LI Jing  XIE Yi
Abstract:Objective To test the values of MR spectroscopy(MRS)and fat saturation(FATSAT)in quantifying fat content in pancreas with 3.OT MR.Methods Thirty-five healthy volunteers were examined with 3 different MR techniques IP/OP,MRS,and FATSAT,to quantify pancreas fat content(FC).The IP/OP result served as a reference standard.Results The IP/OP,FATSAT and MRS detected(8.2±2.0)%,(11.8±4.7)%and(8.8±4.6)%of pancreas fat content,respectively.The IP/OP result correlated with the MRS result(r=0.809,P<0.001),but not with the FATSAT result(r=0.311,P=0.069).Conclusion For 3.0T MRI,MRS technique can quantify pancreas fat content,but FATSAT can not.
Keywords:Magnetic resonance spectroscopy  In-phase and out-of-phase  Fat saturation  Pancreas  Fat content
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