基于西南地区居民EQ-5D-5L量表信效度评价

  目的  探究EQ-5D-5L量表应用于我国西南地区人群中生命质量评价的信度和效度。  方法  采用克朗巴哈α系数（Cronbach’s α）测量量表的内部一致性信度，探索性因子分析结合验证性因子分析测量结构效度、聚敛效度和区分效度。  结果  Cronbach’s α系数为0.857，探索性因子分析提取2个方差累计贡献率为77.311%的公因子，第一公因子代表行动能力、自己照顾自己能力和日常活动能力，第二公因子代表疼痛或不舒服、焦虑或抑郁。验证性因子分析两个公因子的相关性为0.659，第一公因子平均方差变异为0.862且组合信度为0.949，第二公因子的平均方差提取值为0.587且组合信度为0.739，四处走动、自我照顾和日常活动在第一公因子上的载荷分别为0.871、0.945和0.967，疼痛或不舒服、焦虑或沮丧在第二公因子上的载荷分别为0.708和0.820。  结论  EQ-5D-5L在应用于西南地区居民测量生命质量有较好的信度和效度。

Evaluation of Reliability and Validity of EQ-5D-5L Based on Residents in Southwest China

  Objective  To explore the reliability and validity of the EQ-5D-5L scale in the population of southwest China.  Methods  The internal consistency reliability is measured by Cronbach's α coefficient and the structural validity is measured by factor analysis. The difference in health utility value of different characteristic populations is compared by t test and analysis of variance.  Results  Cronbach's α coefficient was 0.857. Exploratory factor analysis extracts two common factors whose cumulative contribution rate is 77.311%. The first common factor represents mobility, self-care and uaual activities. The second common factor represents pain/discomfort and anxiety/depression. The results of confirmatory factor analysis showed that the correlation of the two common factors was 0.659, the average variance of the first common factor was 0.862 and the combination reliability was 0.949, and the average variance extracted of the second common factor was 0.587 and the composite reliability was 0.739. The factor loadings for mobility, self-care and uaual activities on the first common factor were 0.871, 0.945 and 0.967, respectively. The loadings for pain/discomfort and anxiety/depression on the second common factor were 0.708 and 0.820, respectively.  Conclusion  EQ-5D-5L has good reliability and validity when it is applied to the measurement of healthy life quality of residents in Southwest China.