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腹泻型肠易激综合征影响因素与中医体质分型研究
引用本文:龚军.腹泻型肠易激综合征影响因素与中医体质分型研究[J].河南中医药学刊,2014(10):1501-1503.
作者姓名:龚军
作者单位:南京同仁医院,江苏南京211102
基金项目:国家自然科学基金项目(编号:50827530)
摘    要:目的:分析腹泻性肠易激综合征(IBS-D)患者的体质特点,探讨其影响因素与中医体质类型的关系。方法:采用1∶1配对病例对照设计,通过中医体质量表得分判断IBS-D患者的体质类型,比较不同的IBS-D影响因素下患者的体质类型分布特点,并应用条件Logistic回归分析得出不同体质类型者患IBS-D的危险度。结果:IBS-D患者病理性体质类型构成明显高于正常人群(χ^2=-2.790,P〈0.01),以阳虚质、痰湿质、气郁质,气虚质、湿热质为著;女性IBS-D总体患病率高于男性(χ^2=-7.308,P〈0.01),女性人群中,阳虚质、湿热质、气虚质、气郁质人群患IBS-D的危险性分别比平和质人群的发病危险分别高4.531倍、2.805倍、2.574倍和2.335倍;男性痰湿质体质人群患IBS-D的危险性为平和质性人群的1.943倍(OR=1.943);不同年龄、病程、职业对IBS-D的发病无影响。结论:不同性别人群IBS-D的发病与中医体质分析存在相关性,改善患者病理体质可有效预防IBS-D的发生发展。

关 键 词:腹泻型肠易激综合征  体质分型  中医体质量表  Logistic回归分析

Study on the Influential Factors of Diarrhea-Predominant Irritable Bowel Syndrome and Traditional Chinese Medicine Constitution Typing
Gong Jun.Study on the Influential Factors of Diarrhea-Predominant Irritable Bowel Syndrome and Traditional Chinese Medicine Constitution Typing[J].Journal of Henan college of Traditional Chinese Medicine,2014(10):1501-1503.
Authors:Gong Jun
Institution:Gong Jun (Nanjing Tongren Hospital, Nanjing Jiangsu China 211102)
Abstract:Objective: To analyze the constitution features of the patient with diarrhea-predominant irritable bowel syndrome,and investigate the relationship between its influential factors and traditional Chinese medicine constitution typing. Methods: Used a 1∶1 matched case-control design,judged the constitution types in patients with IBS-D through the constitution of TCM scale score,compared the distribution characteristics of TCM constitutional types under the influence factors of patients with IBS-D and analyzed the risk IBS-D patient with different constitution types used by logistic regression analysis. Results: IBS-D patients with pathological constitution types of yang-asthenia,phlegm-dampness,qi-depression,qi-asthenia,dampness-heat significantly higher than the normal population( χ^2=- 2. 790,P〈0. 01); the IBS-D prevalence of women is higher than men( χ^2=- 7. 308,P〈0. 01),the yang-asthenia,dampnessheat,qi-asthenia,qi-depression constitution in female population suffering from IBS-D were more dangerous than gentleness populations,the risk were respectively 4. 531 times,2. 805 times,2. 574 times,and 2. 335 times; And the males with phlegm-dampness constitution suffering from IBS-D were more dangerous than gentleness populations as 1. 943 times( OR = 1. 943); And different age,duration of disease,occupation had no effect on the incidence of IBS-D. Conclusion: The incidence of IBS-D in different gender groups have the correlation with the TCM constitution,improving patient with IBS-D pathological constitution can be effective in preventing the occurrence and development of IBS-D.
Keywords:diarrhea-predominant irritable bowel syndrome  constitutional type  constitution of TCM scale  logistic regression analysis
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