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昆仑雪菊水提液对高血压模型大鼠血脂和血压的影响
引用本文:李永平,赵学慧,杜文琪,洒玉萍,武娟,曹宁丽.昆仑雪菊水提液对高血压模型大鼠血脂和血压的影响[J].甘肃中医,2017,30(6).
作者姓名:李永平  赵学慧  杜文琪  洒玉萍  武娟  曹宁丽
作者单位:青海大学,青海 西宁,810000
摘    要:目的:研究昆仑雪菊对高脂、高盐复合饲料所致高血压模型大鼠血脂、血压的影响。方法:将实验大鼠随机分为空白对照组、模型组和昆仑雪菊治疗组,后2组使用高脂、高盐复合饲料喂养以诱发高血压疾病模型,在造模的同时昆仑雪菊治疗组给予灌胃昆仑雪菊水提物。第8周末测定大鼠血脂、血压变化情况。结果:第8周末模型组已具有高血压的特征,与空白对照组比较差异有统计学意义(P0.05),昆仑雪菊治疗组大鼠血脂、血压较模型组明显降低(P0.05)。结论:昆仑雪菊具有明显延缓高脂高盐复合饮食诱发高血脂高血压发生的进程,具有一定降血脂、降血压作用。

关 键 词:昆仑雪菊水提液  血脂与血压  影响

Effects of Kunlun Chrysanthemum Aqueous Extract on Blood Lipids and Blood Pressure in Hypertensive Rats
LI Yongping,ZHAO Xuehui,DU Wenqi,SA Yuping,WU Juan,CAO Ningli.Effects of Kunlun Chrysanthemum Aqueous Extract on Blood Lipids and Blood Pressure in Hypertensive Rats[J].Gansu Journal of Traditional Chinese Medicine,2017,30(6).
Authors:LI Yongping  ZHAO Xuehui  DU Wenqi  SA Yuping  WU Juan  CAO Ningli
Abstract:Objective:To study the effects of Kunlun chrysanthemum on blood lipids and blood pressure in rat models with hypertension caused by high-fat and high-salt diet. Methods: Experimental rats were randomly divided into blank control group, the model group and Kunlun chrysanthemum treatment group. The latter two groups were given high-fat combined with high-salt diet for inducing hypertension models. The Kunlun chrysanthemum treatment group was given Kunlun chrysanthemum aqueous extract gavage when model was prepared. Changes of blood lipid and blood pressure of the rats were determined at the end of 8th week. Results: Compared with the blank control group, the rats in the model group already have manifested high blood pressure symptoms at the end of 8th week, and the difference was statistically significant (P<0.05). Blood lipid and blood pressure decreased significantly in the Kunlun chrysanthemum treatment group compared with the model group (P<0.05). Conclusion:Kunlun chrysanthemum can significantly delay the process of high blood lipid and high blood pressure induced by high-fat and high-salt diet; it shows certain effects of lowering blood lipid and blood pressure.
Keywords:Kunlun chrysanthemum aqueous extract  blood lipid and blood pressure  effect
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