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黄芪建中汤加减治疗脾胃虚寒型复发性口腔溃疡60例
引用本文:辛自芳.黄芪建中汤加减治疗脾胃虚寒型复发性口腔溃疡60例[J].甘肃中医,2017,30(4).
作者姓名:辛自芳
作者单位:泾川县中医医院,甘肃 泾川,744300
摘    要:目的:观察黄芪建中汤加减治疗脾胃虚寒型复发性口腔溃疡的临床疗效.方法:将120例患者随机分为2组.对照组给予维生素B2、维生素C及左旋咪唑进行治疗,观察组在对照组治疗的基础上给予黄芪建中汤加减治疗.观察2组治疗前后溃疡面积、平均溃疡期、疼痛指数、证候积分及CD3+、CD4+、CD8+及CD4+/CD8+水平的变化情况,并评估临床疗效及用药不良反应.结果:溃疡面积、平均溃疡期、疼痛指数、证候积分及CD3+、CD4+、CD8+及CD4+/CD8+水平治疗前2组比较,差异无统计学意义(P>0.05);治疗后2组均明显降低,组内比较差异有统计学意义(P<0.05),组间比较差异也有统计学意义(P<0.05).总有效率观察为91.67%,对照组为66.67%,2组比较差异有统计学意义(P<0.05).复发率观察组为6.67%,对照组为20.00%,2组比较差异有统计学意义(P<0.05).结论:黄芪建中汤加减治疗脾胃虚寒型复发性口腔溃疡,疗效显著,安全性好.

关 键 词:口腔溃疡  复发性  脾胃虚寒型  黄芪建中汤

Study of Modified HuangQi JianZhong Tang in the Treatment of 60 Cases of Recurrent Oral Ulcer of Spleen and Stomach Deficiency-Cold Pattern
XIN Zifang.Study of Modified HuangQi JianZhong Tang in the Treatment of 60 Cases of Recurrent Oral Ulcer of Spleen and Stomach Deficiency-Cold Pattern[J].Gansu Journal of Traditional Chinese Medicine,2017,30(4).
Authors:XIN Zifang
Abstract:Objective: To observe the clinical effects of modified HuangQi JianZhong Tang in the treatment of recurrent oral ulcer of spleen and stomach deficiency-cold pattern. Methods: 120 patients were randomly divided into two groups. The control group was treated by vitamin B2, vitamin C and levamisole. Based on the treatment of the control group, the observation group was also given modified HuangQi JianZhong Tang. Ulcer area, mean ulcer duration, pain index, syndrome scores and level changes of CD3+, CD4+, CD8+ and CD4+/CD8+ of two groups were observed before and after treatment. And the clinical effects and adverse drug reactions of two groups were evaluated. Results: Compared the ulcer area, mean ulcer duration, pain index, syndrome scores and levels of CD3+, CD4+, CD8+ and CD4+/CD8+ of two groups before treatment, the differences were not statistically significant (P>0.05);All indexes above decreased in two groups after treatment, compared within groups, the differences were statistically significant (P<0.05); compared between two groups, the differences were also statistically significant(P<0.05). The total effective rate of the observation group was 91.67% , and that of the control group was 66.67% , compared between two groups, the differences were statistically significant (P<0.05). The recurrence rate of the observation group was 6.67%, and that of the control group was 20.00%, compared between two groups, the differences were statistically significant (P<0.05). Conclusion: Modified HuangQi JianZhong Tang has significant treatment effects and good safety in the treatment of recurrent oral ulcer spleen and stomach type of deficiency-cold pattern.
Keywords:oral ulcer  recurrent  spleen and stomach deficiency-cold pattern  HuangQi JianZhong Tang
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