| 淮山药多糖的免疫调节作用研究 |
| |
| 引用本文： | 徐增莱,汪琼,赵猛,徐琴,贾成森,史云云.淮山药多糖的免疫调节作用研究[J].时珍国医国药,2007,18(5):1040-1041. |
| |
| 作者姓名： | 徐增莱 汪琼 赵猛 徐琴 贾成森 史云云 |
| |
| 作者单位： | 江苏省中国科学院植物研究所·南京中山植物园,江苏,南京,210014 |
| |
| 基金项目： | 江苏省自然科学基金资助项目(No.BK2003065) |
| |
| 摘 要： | 目的探讨淮山药粗多糖对小鼠的免疫调节作用。方法小鼠灌胃给予不同剂量(200,400和800 mg/kg)的淮山药多糖,1次/d,连续8 d,进行ConA诱导的小鼠脾淋巴细胞转化实验(MTT法)、测定血清溶血素测定(半数溶血值法)、小鼠碳廓清实验。结果山药多糖具有增强小鼠淋巴细胞增殖能力的作用,促进小鼠抗体生成的作用和增强小鼠碳廓清能力的作用。结论淮山药多糖具有一定的免疫功能增强作用。
|
| 关 键 词： | 淮山药 多糖 免疫调节 |
| 文章编号： | 1008-0805(2007)05-1040-02 |
| 修稿时间： | 2006年9月6日 |
Test on the Immunity- moderating Function of Dioscorea oppostita Thunb. Polysaccharide |
| |
| XU Zeng-lai,WANG Qiong,ZHAO Meng,XU Qin,JIA Cheng-sen,SHI Yun-yun.Test on the Immunity- moderating Function of Dioscorea oppostita Thunb. Polysaccharide[J].Lishizhen Medicine and Materia Medica Research,2007,18(5):1040-1041. |
| |
| Authors: | XU Zeng-lai WANG Qiong ZHAO Meng XU Qin JIA Cheng-sen SHI Yun-yun |
| |
| Abstract: | Objective To investigate the immunologic enhancement of Dioscorea opposita Thunb.polysaccharide.Methods Dioscorea opposita Thunb.polysaccharide in different dosages(200,400,800 mg/kg)were given by IG for 8 d.A series of tests were carried out,such as the spleen lymph cells transformation of Con A inducing method(MTT method),hemolytic test of blood serum and hem chrome and mouse carbon test.Results The results showed that Dioscorea opposita Thunb.polysaccharide was significant to Con A induced mice Lymphocyte transformation test;HC50 raised in all three concentrations;ratio of monocytemacrophage carbon grain elimination has significant changes to the control.Conclusion Dioscored opposita Thunb.polysaccharide possesses a potential effect of immune regulation. |
| |
| Keywords: | Dioscorea opposita Thunb Polysaccharide Immunity moderation |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
