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狗皮膏皮肤用药安全性实验研究
引用本文:曾勇,赵贵琴,陈怀斌,李帆帆,孟宪丽.狗皮膏皮肤用药安全性实验研究[J].时珍国医国药,2012,23(2):375-376.
作者姓名:曾勇  赵贵琴  陈怀斌  李帆帆  孟宪丽
作者单位:1. 成都中医药大学 中药材标准化教育部重点实验室,中药资源系统研究与开发利用省部共建国家重点实验室培育基地,四川 成都 610075
2. 四川省天全县中医医院 625500
基金项目:国家“十一五”科技支撑计划
摘    要:目的探讨狗皮膏皮肤用药安全性研究。方法对家兔进行皮肤急性毒性实验、皮肤刺激性实验,对豚鼠进行皮肤过敏实验。结果狗皮膏对家兔皮肤未引起急性毒性反应和刺激性反应,对豚鼠无致敏作用。结论狗皮膏是一种安全性较好的外用药。

关 键 词:狗皮膏  皮肤急性毒性  皮肤刺激性  皮肤过敏性

Experimental Study on the Safety of Gou - pi Plaster
ZENG Yong , ZHAO Gui-qin , CHEN Huai-bin , LI Fan-fan , MENG Xian-li.Experimental Study on the Safety of Gou - pi Plaster[J].Lishizhen Medicine and Materia Medica Research,2012,23(2):375-376.
Authors:ZENG Yong  ZHAO Gui-qin  CHEN Huai-bin  LI Fan-fan  MENG Xian-li
Institution:1(1.Chengdu University of Traditional Chinese Medicine,Key Laboratory of Standardization of Chinese Herbal Medicines,Ministry of Education,Chengdu 610075,China;2.The Traditional Chinese Medicine Hospital of Tianquan County,Tianquan,Sichuan 625500,China)
Abstract:Objective To discuss the safety of Gou-pi plaster on skin treatment. Methods The skin acute toxicity experiment and skin irritating quality experiment were carried on the rabbits;the skin sensibility experiment was carried on the guinea pigs. Results Gou-pi plaster did not cause acute toxic reaction and excitant reaction on rabbit skin,and had no sensitization effect on guinea pigs. Conclusion Gou-pi plaster has food security for external use.
Keywords:Gou-pi plaster  Skin acute toxicity test  Skin irritation  Skin allergy
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