| 4种中药体外抗结核分枝杆菌H37RV的研究 |
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| 引用本文： | 白洁,孙海峰,陈翔飞.4种中药体外抗结核分枝杆菌H37RV的研究[J].时珍国医国药,2007,18(1):77-78. |
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| 作者姓名： | 白洁 孙海峰 陈翔飞 |
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| 作者单位： | 1. 深圳清华大学研究院,广东,深圳,518057;清华大学化学系,北京,100084
2. 深圳清华大学研究院,广东,深圳,518057 |
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| 摘 要： | 目的研究中药夏枯草、积雪草、筋骨草和青蒿素的体外抗结核分枝杆菌H37RV的活性。方法采用改良罗氏固体培养基试管培养法进行活性检测。结果夏枯草醇提物抗结核效果明显;积雪草苷片、筋骨草及青蒿素均无效。结论夏枯草醇提物抗结核菌效果优于水提物;积雪草醇提物有微弱抑制结核杆菌活性,但其有效成分可能不是积雪草苷;青蒿素及二氢青蒿素无抑制结核分枝杆菌的活性。
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| 关 键 词： | 夏枯草 积雪草 筋骨草 青蒿素 抗结核 |
| 文章编号： | 1008-0805(2007)01-0077-02 |
| 修稿时间： | 2006年3月14日 |
Studies on the Anti -mycobaterium Tuberculosis Activity of 4 Chinese Medicinal Herbs |
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| BAI Jie,SUN Hai-feng,CHEN Xiang-fei.Studies on the Anti -mycobaterium Tuberculosis Activity of 4 Chinese Medicinal Herbs[J].Lishizhen Medicine and Materia Medica Research,2007,18(1):77-78. |
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| Authors: | BAI Jie SUN Hai-feng CHEN Xiang-fei |
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| Abstract: | Objective To explore the effective anti-mycobaterium tuberculosis activity of Prunella vulgaris L.,Centella asiatica(L.) Urb,Ajuga decumbens Thunb.and artemisini.Methods Anti-mycobaterium tuberculosis activities in vitro of the extracts were performed.Results The alcoholic extract of Prunella vulgaris L.had obviously anti-mycobaterium tuberculosis effect,while the extract of Ajuga decumbens Thunb.and artemisinin were of no effect against tuberclosi.Conclusion The results suggested that the anti-mycobaterium tuberculosis activity of Prunella vulgaris L.alcoholic extract was more significant than water-soluble extract of it,and asiaticosides were likely to be noneffective constituents of Centella asiatica(L.) Urb to tubercle bacillus. |
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| Keywords: | Prunella vulgaris L Centella asiatica(L ) Urb Ajuga decumbens Thunb Artemisinin Anti-mycobaterium tuberculosis |
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