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慢性阻塞性肺疾病急性加重期Ⅱ型呼吸衰竭与肝功能异常的相关性研究
引用本文:杨镋灵,Yang Tangling.慢性阻塞性肺疾病急性加重期Ⅱ型呼吸衰竭与肝功能异常的相关性研究[J].中国中医药现代远程教育,2009,7(5):12-13.
作者姓名:杨镋灵  Yang Tangling
作者单位:四川省广安市人民医院呼吸内科,638000
摘    要:目的探讨慢性阻塞性肺疾病急性加重期(AECOPD)II型呼吸衰竭患者低氧血症、感染与肝功能异常的相关性研究。方法回顾分析我院256列AECOPD致II型呼吸衰竭患者,分别对其进行治疗前后检测胸部X线片、外周血白细胞计数、中性粒细胞百分比、肝功能及动脉血气分析,并对治疗前后检验结果进行比较分析。结果AECOPD患者治疗后胸部X线片、动脉血氧分压(PaO2)、外周血白细胞、中性粒细胞百分比和肝功能各参数值较治疗前均有明显改善(P〈0.01);随pH值、PaO2、PaCO2指标的改善及感染的控制,肝功能亦逐渐恢复至正常。结论AECOPDII型呼吸衰竭低氧血症、感染对肝脏功能有明显的损害;给予抗感染,纠正低氧血症、二氧化碳潴留及酸中毒,保肝、支持疗法等治疗后随着感染的控制、呼吸衰竭的纠正肝功能可恢复正常。

关 键 词:慢性阻塞性肺疾病急性加重期  Ⅱ型呼吸衰竭  肝功能损害

To Study the Relationship Between Abnormity of Liver Function in Elderly Patients with Chronic Obstructive Pulmonary Disease
Abstract:Objective To study the relationship between hyoxemia, infection and abnormity of liver function in elderly patients with chronic obstructive pulmonary disease(COPD). Methods Retrospective analysis of 256 cases of type 11 respiratory failure of chronic obsmactive pulmonary diseases (COPD) in our hospital. The peripheral white blood cell count, liver function and arterial blood gas analysis were measured in patients with COPD, and X-ray of chest in every group were made. The association between the parameters of blood gases and liver function were analyzed by from beginning to end comparison. Resu I t These parameters of peripheral white blood cell count, liver function and arterial blood gas analysis were remarkably improved (P〈 0.01); The recovery of liver function followed these parameters. Coneclusion It is remarkably harmful for liver function of type Ⅱ respiratory failure of chronic obstructive pulmonary diseases (COPD) that hyoxemia and infection; Treatment of anti infection, protection of liver function and support therapy of nutrition, then it can recall normal that liver function of ype Ⅱ respiratory failure of chronic obstructive pulmonary diseases (COPD).
Keywords:acute exacerbation of chronic obstructive pulmonary diseases (AECOPD)  type Ⅱ respiratory falhire  lesion of liver function
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