| 桑白皮多糖对小鼠实验性肝损伤的保护作用 |
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| 引用本文： | 黄强,江丽霞,曾靖.桑白皮多糖对小鼠实验性肝损伤的保护作用[J].中国中医药现代远程教育,2014(3):155-156. |
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| 作者姓名： | 黄强 江丽霞 曾靖 |
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| 作者单位： | [1]江西省新余市新钢中心医院,新余338001 [2]江西省赣南医学院第一附属医院检验科,赣州341000 [3]江西省赣南医学院药学院,赣州341000 |
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| 摘 要： | 目的 研究桑白皮多糖（PCM）对小鼠实验性肝损伤的保护作用.方法 采用四氯化碳（CCl4）、扑热息痛（AAP）、硫代乙酰胺（TAA）致小鼠急性肝损伤模型,测定小鼠血清ALT、AST活性.结果 PCM对CCl4、AAP所致小鼠实验性肝损伤有明显保护作用.但PCM对TAA所致小鼠实验性肝损伤无明显的保护作用.结论 PCM可明显降低CCl4、AAP致小鼠急性肝损伤模型血清ALT、AST活性,而对TAA致小鼠急性肝损伤模型血清ALT、AST活性无明显作用.
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| 关 键 词： | 桑白皮多糖 肝损伤 保肝作用 血清谷丙转氨酶、谷草转氨酶 中药 |
Protective effects of Morus alba L polysaccharide on experimental liver injuries |
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| Chen Jianglin Jiang Lixia Zeng Jing.Protective effects of Morus alba L polysaccharide on experimental liver injuries[J].Chinese Medicine Modern Distance Education of China,2014(3):155-156. |
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| Authors: | Chen Jianglin Jiang Lixia Zeng Jing |
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| Institution: | Chen Jianglin Jiang Lixia Zeng Jing (1 Xiyu city new steel centra hospital of Ganzhou, Jiangxi province, Xiyu,341000 china;2 The first affited hospital of Gannan medical university,Jiangxi province, Ganzhou,341000,China; 3 Gannan Medical College, Ganzhou 341000,china) |
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| Abstract: | Objective To study the protective effect of Morus alba L polysaccharide on experimental liver injuries. M; The activity of serum ALT,AST were measured in the model mice of liver injury induced by carbon tetraehloride（CCl4）, Acetaminophen（AAP） and Thioacetamide （TAA）. Results The serum ALT, AST activity was significantly lowered in the model mice of liver injure induced by CCl4 AAP and TAA after Morus alba L polysaccharide was given orally. Condgsion Morus alba L polysaccharide exhibited protective effect on experimental liver injuries. |
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| Keywords: | Morus alba L polysaccharide Liver injuries Protective liver ALT AST Chinese herb |
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