罗玲主任医师治疗肺结节用药规律的聚类分析

目的基于聚类分析方法,探讨罗玲主任医师治疗肺结节的用药和配伍规律。方法以2018年1月—2019年6月在罗玲主任医师门诊就诊的130例肺结节患者为研究对象,对罗玲主任医师治疗肺结节常用药物进行频数和聚类分析,探索其治疗肺结节的常用药物和配伍规律。结果罗玲主任医师治疗肺结节使用最多的药物为山药、半夏、夏枯草、莪术、玄参、太子参、贝母、皂角刺、山慈菇、鳖甲、红花、桔梗。聚类分析显示常用药物可分为5类:燥湿化痰、降气宽中类,清热散结、消痰利咽类,软坚散结、补气活血类,补益脾肺、止咳化痰,活血祛瘀、敛肺滋肾类。结论罗玲主任医师认为,肺结节分五种证候类型,一型以痰湿阻肺,肺气上逆为主,当以燥湿化痰、降气宽中为主要治则;二型以痰热阻于肺与咽喉为主,当以清热散结、消痰利咽为主;三型以痰结血瘀为主,重在软坚散结、补气活血为主;四型以肺脾两虚为主,主要以补益脾肺、止咳化痰为治则;五型以肺肾两虚为主,治则以活血祛瘀、敛肺滋肾为主。

Clustering analysis of the rule of using medicine for pulmonary nodules by chief physician luo ling

Objective based on the cluster analysis method,to explore the rule of medication and compatibility of chief physician luo ling in the treatment of pulmonary nodules.Methods from January 2018 to June 2019,130 patients with pulmonary nodules who visited the outpatient department of chief physician luo ling were selected as the study objects.The frequency and clustering analysis were conducted on the commonly used drugs of chief physician luo ling for the treatment of pulmonary nodules,so as to explore their commonly used drugs and compatibility rules for the treatment of pulmonary nodules.Results Chinese yam,pinellia tuber,prunella curcuma,rhizoma zedoariae,radix dioscoreae,radix pseudostellariae,fritillaria,saponiana SPP.Cluster analysis showed that common drugs can be divided into 5 categories:dry dampness and phlegm removing,middle category of reducing qi width,clearing heat and dispersive knot,eliminating phlegm and benefiting pharynx,soft and firm dispersive knot,tonifying qi and activating blood circulation,soft and firm dispersive knot,tonifying qi and activating blood circulation,activating blood circulation removing stasis,astringent lung and nourishing kidney.Conclusion chief physician luo ling believes that pulmonary nodules can be classified into five syndromes.Type 1 is mainly phlegm-dampness obstructing lung,lung qi is inverse,and dryness dampness removing phlegm and reducing qi width is the main treatment.The second type is mainly phlegm and heat resistance in the lung and throat,when the heat dissipation,phlegm benefit pharynx.The third type is mainly phlegm and blood stasis,mainly soft and firm,invigorating qi and activating blood.The fourth type is mainly characterized by deficiency of lung and spleen,which is mainly treated by invigorating spleen and lung,relieving cough and eliminating phlegm.The fifth type is mainly caused by two deficiency of lung and kidney.