| 抗肿瘤前药的研究进展 |
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| 引用本文： | 张莉,马媛.抗肿瘤前药的研究进展[J].中国民族民间医药杂志,2009(3). |
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| 作者姓名： | 张莉 马媛 |
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| 作者单位： | [1]山东省滕州市中医医院 [2]山东省滕州市中心人民医院 |
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| 摘 要： | 前药保持或增强原药的药效,同时又克服了原药的缺点。前体药物通过对抗肿瘤原药的化学结构或药物剂型给予一定修饰,大大克服了化疗药物的缺点,开辟了一条抗肿瘤药物的新途径,现对其研究进展和应用做一综述。
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| 关 键 词： | 前药 靶向药物 抗肿瘤药物 |
The new progress of antitum prodrug |
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| ZHANG Li MA Yuan.The new progress of antitum prodrug[J].Chinese Journal of Ethnomedicine and Ethnopharmacy,2009(3). |
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| Authors: | ZHANG Li MA Yuan |
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| Institution: | 1Shandong Tengzhou Of Traditional Chinese Medicine;Shandong;Tengzhou;277500;2Shandong Tengzhou Municipal Central Hospital;277500 |
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| Abstract: | The prodrugs can retain or improve effects of the parent drug ,meanwhile,overcome the drawback of the parent drug. Prodrug, which is from the modification of active drug constructure or pharmaceutical dosage form, greatly overcome the defect of chemotherapy agent and open a new way in antitumor drug . At present, Several antitumor prodrugs have been reviewed. |
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| Keywords: | prodrugs targeting drugs antitumor drug |
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