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葛根降糖胶囊水提醇沉工艺的研究
引用本文:陈建真,陈建明.葛根降糖胶囊水提醇沉工艺的研究[J].世界科学技术,2006,8(6):46-49.
作者姓名:陈建真  陈建明
作者单位:[1]浙江中医药大学,杭州310053 [2]浙江省中医院,杭州310006
摘    要:目的:研究葛根降糖胶囊水提醇沉的工艺条件。方法:选用L9(34)正交表,以提取葛根素总量为评价指标,葛根素含量测定采用高效液相色谱法(HPLC)。结果:因素A(煎煮次数)和B(提取时间)对水提工艺有显著影响,煎煮工艺确定为A3B2C3。因素A(醇沉浓度)对醇沉工艺有显著影响,醇沉工艺确定为A3B3C1。结论:该水提醇沉工艺科学、合理。

关 键 词:葛根降糖胶囊  水提醇沉  正交试验  葛根素
收稿时间:2006-03-13
修稿时间:2006-05-28

Water Extracting and Alcohol Precipitation Techniques for Gegenjiangtang Capsule Making
Chen Jianzhen,Chen Jianming.Water Extracting and Alcohol Precipitation Techniques for Gegenjiangtang Capsule Making[J].World Science and Technology(Modernization of Traditional Chinese Medicine),2006,8(6):46-49.
Authors:Chen Jianzhen  Chen Jianming
Institution:Zhejiang Unversity of TCM, Hangzhou ,310053; Zhejiang Provincial Hospital of TCM, Hangzhou , 310006
Abstract:This paper introduces a technical process of water extracting and alcohol precipitation for gegenjiangtang capsule making.An orthogonal design L_9 (3~4) is used in both water extracting and alcohol precipitation.The total concentration of puerarin is measured to assess the efficacy of water extracting and alcohol precipitation techniques.The findings suggest that the total concentration of puerarin is noticeably affected by factor A (times of extraction) and B (timing of extraction ) in water extracting,and by factor A (concentration of alcohol precipitation) in alcohol precipitation.The most desira- ble setting for water extracting is A_3B_2C_3,and for alcohol precipitation A_3B_3C_1.It is believed that the process of water extracting and alcohol precipitation is built on a scientific and rational basis.
Keywords:Gegenjiangtang capsules  water extracting/alcohol precipitation  orthogonal test  puerarin
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