| 木通肾毒性的临床特点及实验研究概况 |
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| 引用本文： | 胡锦官,龙绍疆,顾健.木通肾毒性的临床特点及实验研究概况[J].世界科学技术,2003,5(2):31-36. |
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| 作者姓名： | 胡锦官 龙绍疆 顾健 |
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| 作者单位： | 胡锦官（成都中医药大学药学院,成都,610075）
龙绍疆（成都中医药大学药学院,成都,610075）
顾健（成都中医药大学药学院,成都,610075） |
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| 摘 要： | 关地木通的肾毒性在国内外引起了极大关注。本文对关木通进行了本草学考证，并对关木通肾脏损害的临床特点以及近年来在动物模型、毒性机理和药代动力学等方面的实验研究进行了综述。
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| 关 键 词： | 关地木通 肾毒性 药代动力学 毒性机理 动物模型 马兜铃酸 中药 |
| 修稿时间： | 2002年12月6日 |
Clinical Characteristics of Nephrotoxicity of Caulis Aristolochiae Manshuriensis and Related Experimental Research |
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| Hu Jinguan,Long Shaojiang and Gu Jian.Clinical Characteristics of Nephrotoxicity of Caulis Aristolochiae Manshuriensis and Related Experimental Research[J].World Science and Technology(Modernization of Traditional Chinese Medicine),2003,5(2):31-36. |
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| Authors: | Hu Jinguan Long Shaojiang and Gu Jian |
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| Abstract: | The nephrotoxicity of Caulis Aristolochiae Manshuriensis has got more and more attention in China and abroad. This article makes the textual research of Caulis Aristolochiae Manshuriensis from the viewpoint of herbalism and summarizes the clinical characteristics of its nephrotoxicity as well as its experimental research carried out in animal models, toxicity mechanisms and pharmacokinetics in recent years. |
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| Keywords: | Caulis aristolochiae manshuriensis nephrotoxicity aristolochia acid animal model pharmacokinetics |
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